Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca<sup>2+</sup> homeostasis.

Kong, Anqi; Zhang, Yao; Ning, Bo; Li, Kongdong; Ren, Zhen; Dai, Shuya; Chen, Dongfeng; Zhou, Yang; Gu, Jie; Shi, Haifeng

Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca²⁺ homeostasis.

Kong, Anqi; Zhang, Yao; Ning, Bo; Li, Kongdong; Ren, Zhen; Dai, Shuya; Chen, Dongfeng; Zhou, Yang; Gu, Jie; Shi, Haifeng.

Afiliación

Kong A; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Zhang Y; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Ning B; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Li K; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Ren Z; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Dai S; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Chen D; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Zhou Y; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Gu J; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China. Electronic address: 1000004531@ujs.edu.cn.
Shi H; School of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China; School of Food and Biological Engineering, Zhenjiang, Jiangsu, 212013, China. Electronic address: shihf@ujs.edu.cn.

Chem Biol Interact ; 348: 109649, 2021 Oct 01.

Article en En | MEDLINE | ID: mdl-34516972

Asunto(s)

Cadmio/farmacología; Proteínas Portadoras/metabolismo; Retículo Endoplásmico/metabolismo; Homeostasis/efectos de los fármacos; Lisosomas/efectos de los fármacos; Lisosomas/metabolismo; Triglicéridos/metabolismo; Retículo Endoplásmico/efectos de los fármacos; Células Hep G2; Humanos; ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/metabolismo

Palabras clave

Cadmium; Endoplasmic reticulum Ca(2+); Lysosomal acidity; Microsomal triglyceride transfer protein; Triglycerides

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Cadmio / Proteínas Portadoras / Retículo Endoplásmico / Homeostasis / Lisosomas Límite: Humans Idioma: En Revista: Chem Biol Interact Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda

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