Staphylococcus haemolyticus meningitis and bacteremia in an allogenic stem cell transplant patient.

Bryce, Aliya N; Doocey, Richard; Handy, Rupert

Bryce, Aliya N; Doocey, Richard; Handy, Rupert.

Afiliación

Bryce AN; Department of Infectious Diseases, Middlemore Hospital, 100 Hospital Road, Auckland 2025, New Zealand.
Doocey R; Department of Haematology, Auckland City Hospital, 2 Park Road, Grafton, Auckland 1023, New Zealand.
Handy R; Department of Infectious Diseases, Auckland City Hospital, 2 Park Road, Grafton, Auckland 1023, New Zealand.

IDCases ; 26: e01259, 2021.

Article en En | MEDLINE | ID: mdl-34485080

RESUMEN

Staphylococcus haemolyticus is a rare cause of bacterial meningitis and most commonly occurs as a nosocomial infection in patients' post-neurosurgery. We report a patient post-allogenic stem cell transplant, with no prior history of neurosurgical procedures, who developed S. haemolyticus meningitis and bacteremia following central catheter-related bloodstream infection. The patient failed therapy with vancomycin and daptomycin but was successfully treated with a prolonged course of linezolid. We review the pharmacological management of coagulase negative Staphylococcus (CoNS) meningitis, with a focus on the pharmacokinetic properties of vancomycin, daptomycin and linezolid within the cerebrospinal fluid (CSF).

Palabras clave

coagulase-negative Staphylococcus; daptomycin; immunosuppression; linezolid; meningitis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IDCases Año: 2021 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Países Bajos

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