Co-operative binding of SKP1, Cullin1 and Cullin7 to FBXW8 results in Cullin1-SKP1-FBXW8-Cullin7 functional complex formation that monitors cellular function of ß-TrCP1.

Islam, Sehbanul; Dutta, Parul; Chopra, Kriti; Sahay, Osheen; Rapole, Srikanth; Chauhan, Radha; Santra, Manas Kumar

Islam, Sehbanul; Dutta, Parul; Chopra, Kriti; Sahay, Osheen; Rapole, Srikanth; Chauhan, Radha; Santra, Manas Kumar.

Afiliación

Islam S; Molecular Oncology Laboratory, National Centre for Cell Science, NCCS Complex, Ganeshkhind Road, Pune, Maharashtra 411007, India; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, Maharashtra 411007, India.
Dutta P; Molecular Oncology Laboratory, National Centre for Cell Science, NCCS Complex, Ganeshkhind Road, Pune, Maharashtra 411007, India; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, Maharashtra 411007, India.
Chopra K; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, Maharashtra 411007, India; Laboratory of Structural Biology, National Centre for Cell Science, Pune, Maharashtra 411007, India.
Sahay O; Molecular Oncology Laboratory, National Centre for Cell Science, NCCS Complex, Ganeshkhind Road, Pune, Maharashtra 411007, India; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, Maharashtra 411007, India; Proteomics Laboratory, National Centre for Cell Science,
Rapole S; Proteomics Laboratory, National Centre for Cell Science, Pune, Maharashtra 411007, India.
Chauhan R; Laboratory of Structural Biology, National Centre for Cell Science, Pune, Maharashtra 411007, India.
Santra MK; Molecular Oncology Laboratory, National Centre for Cell Science, NCCS Complex, Ganeshkhind Road, Pune, Maharashtra 411007, India. Electronic address: manas@nccs.res.in.

Int J Biol Macromol ; 190: 233-243, 2021 Nov 01.

Article en En | MEDLINE | ID: mdl-34478796

Asunto(s)

Proteínas Cullin/metabolismo; Proteínas F-Box/metabolismo; Complejos Multiproteicos/metabolismo; Proteínas Quinasas Asociadas a Fase-S/metabolismo; Proteínas con Repetición de beta-Transducina/metabolismo; Movimiento Celular; Proteínas Cullin/química; Proteínas F-Box/química; Humanos; Células MCF-7; Unión Proteica; Estabilidad Proteica; Proteolisis; Proteínas Quinasas Asociadas a Fase-S/química; Especificidad por Sustrato; beta Catenina/metabolismo; Proteínas con Repetición de beta-Transducina/química

Palabras clave

Cell migration; Co-operative binding; F-box protein; Gel filtration; SCF complex

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Cullin / Proteínas F-Box / Proteínas con Repetición de beta-Transducina / Proteínas Quinasas Asociadas a Fase-S / Complejos Multiproteicos Límite: Humans Idioma: En Revista: Int J Biol Macromol Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos

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