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Chikungunya in Guerrero, Mexico, 2019 and Evidence of Gross Underreporting in the Region.
Nunez-Avellaneda, Daniel; Tangudu, Chandra; Barrios-Palacios, Jacqueline; Salazar, Ma Isabel; Machain-Williams, Carlos; Cisneros-Pano, Jonathan; McKeen, Lauren A; Blitvich, Bradley J.
Afiliación
  • Nunez-Avellaneda D; College of Veterinary Medicine, Iowa State University, Ames, Iowa.
  • Tangudu C; College of Veterinary Medicine, Iowa State University, Ames, Iowa.
  • Barrios-Palacios J; National Institute of Medical Sciences and Nutrition Salvador Zubirán, Experimental Pathology Section, Ciudad de México, México.
  • Salazar MI; Laboratorio de Virología e Inmunovirología, Depto. Microbiología Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional, Ciudad de México, México.
  • Machain-Williams C; Laboratorio de Arbovirologia, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi," Universidad Autonoma de Yucatan, Merida, Yucatan, Mexico.
  • Cisneros-Pano J; Laboratorio de Microbiología Médica, Universidad Autonoma de Guerrero, Chilpancingo, Guerrero, México.
  • McKeen LA; College of Liberal Arts and Sciences, Iowa State University, Ames, Iowa.
  • Blitvich BJ; College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Am J Trop Med Hyg ; 105(5): 1281-1284, 2021 10 30.
Article en En | MEDLINE | ID: mdl-34460419
The local public health authorities reported nine cases of chikungunya in Mexico in 2019, none of which occurred in Guerrero, a coastal state in the southwest. To test the hypothesis that chikungunya is grossly underreported in Mexico, acute sera were collected from 639 febrile patients from low-income households in Guerrero in 2019 and serologically assayed for chikungunya virus (CHIKV). Analysis of the sera by plaque reduction neutralization test revealed that 181 (28.3%) patients were seropositive for CHIKV. To identify patients with acute CHIKV infections, a subset of serum samples were tested for CHIKV-specific IgM by ELISA. Serum samples from 21 of 189 (11.1%) patients were positive. These patients met the chikungunya case definition established by the WHO. In conclusion, we provide evidence that CHIKV remains an important public health problem in Mexico and that the true number of cases is severely underestimated.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina M / Virus Chikungunya / Vigilancia en Salud Pública / Fiebre Chikungunya / Exactitud de los Datos Tipo de estudio: Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Mexico Idioma: En Revista: Am J Trop Med Hyg Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina M / Virus Chikungunya / Vigilancia en Salud Pública / Fiebre Chikungunya / Exactitud de los Datos Tipo de estudio: Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Mexico Idioma: En Revista: Am J Trop Med Hyg Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos