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Assessment of Subclinical Psychotic Symptoms in Patients with Rheumatoid Arthritis and Spondyloarthritis.
Prados-Ojeda, Juan L; Luque-Luque, Rogelio; Gordillo-Urbano, Rafael M; Guler, Ipek; López-Medina, Clementina; Collantes-Estévez, Eduardo; Escudero-Contreras, Alejandro.
Afiliación
  • Prados-Ojeda JL; Mental Health Department, Reina Sofia University Hospital, 14004 Cordoba, Spain.
  • Luque-Luque R; Morphological and Socio-Sanitary Sciences, University of Cordoba, 14004 Cordoba, Spain.
  • Gordillo-Urbano RM; Maimonides Institute of Biomedical Research of Córdoba (IMIBIC), 14004 Cordoba, Spain.
  • Guler I; Mental Health Department, Reina Sofia University Hospital, 14004 Cordoba, Spain.
  • López-Medina C; Morphological and Socio-Sanitary Sciences, University of Cordoba, 14004 Cordoba, Spain.
  • Collantes-Estévez E; Maimonides Institute of Biomedical Research of Córdoba (IMIBIC), 14004 Cordoba, Spain.
  • Escudero-Contreras A; Mental Health Department, Reina Sofia University Hospital, 14004 Cordoba, Spain.
J Clin Med ; 10(16)2021 Aug 04.
Article en En | MEDLINE | ID: mdl-34441756
Inflammatory and autoimmune processes have been associated with the onset of depressive and psychotic symptoms. Rheumatoid arthritis (RA) and spondyloarthritis (SpA) are rheumatic diseases with an inflammatory etiology. A high prevalence of depressive and anxiety-related comorbidity has been reported for both diseases, with no evidence of a greater prevalence of psychosis. The objective of the present study was to evaluate for the first time subclinical psychotic symptoms in patients with RA and SpA. This is a cross-sectional, single-center study including RA and SpA patients, as well as healthy controls. Abnormal psychotic experiences (positive, negative, and depressive symptoms) were evaluated using the Community Assessment of Psychic Experiences (CAPE-42). Functional capacity was evaluated using the Short-Form Health Survey SF-12. We compared the CAPE and SF-12 scores between the three groups. We recruited 385 individuals: 218 with RA, 100 with SpA, and 67 healthy controls. According to the CAPE scale, the frequency of subclinical psychotic symptoms was greater in patients than in healthy controls (RA, 1.90 vs. 1.63, p < 0.001; SpA, 1.88 vs. 1.63, p = 0.001). Distress was also greater in patients than in controls owing to the presence of symptoms. No differences were observed between the three groups for the mental dimension scores in the SF-12 Health Survey (43.75 in RA, 45.54 in SpA, and 43.19 in healthy controls). Our findings point to a greater prevalence of subclinical psychotic symptoms in patients with RA and patients with SpA than in the general population. The results suggest an association between inflammation and depression/subclinical psychotic symptoms.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza