A chemiluminescence sensor array for discrimination of seven toxicants.

Zhou, Ziqi; Gong, Yige; Zhang, Chao; Niu, Weifen

Zhou, Ziqi; Gong, Yige; Zhang, Chao; Niu, Weifen.

Afiliación

Zhou Z; School of Forensic Medicine, Shanxi Medical University, Jinzhong, China.
Gong Y; School of Forensic Medicine, Shanxi Medical University, Jinzhong, China.
Zhang C; School of Forensic Medicine, Shanxi Medical University, Jinzhong, China.
Niu W; School of Forensic Medicine, Shanxi Medical University, Jinzhong, China.

Luminescence ; 36(8): 1997-2003, 2021 Dec.

Article en En | MEDLINE | ID: mdl-34432356

RESUMEN

A chemiluminescence (CL) sensor array was developed based on 11 CL systems cross-combined by three luminescence reagents and four oxidants. Using the CL sensor array, we measured seven toxicants, including morphine, ketamine, diazepam, chlorpromazine, strychnine, paraquat, and fenpropathrin, which represent psychotropic drugs, sedatives and hypnotics, rodenticides, herbicides, and insecticides, respectively. The CL response pattern or 'fingerprints' were obtained for a given compound on the sensor array and then discriminated through principal component analysis. The established sensor array has been applied to real-life samples and the results showed that it possesses excellent discrimination.

Asunto(s)

Sustancias Peligrosas; Luminiscencia

Palabras clave

chemiluminescence (CL); discrimination; principal component analysis (PCA); sensor array; toxicants

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sustancias Peligrosas / Luminiscencia Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Luminescence Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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