Your browser doesn't support javascript.
loading
The accuracy of prostate cancer diagnosis in biopsy-naive patients using combined magnetic resonance imaging and transrectal ultrasound fusion-targeted prostate biopsy.
Uno, Hiromi; Taniguchi, Tomoki; Seike, Kensaku; Kato, Daiki; Takai, Manabu; Iinuma, Koji; Horie, Kengo; Nakane, Keita; Koie, Takuya.
Afiliación
  • Uno H; Department of Urology, Chuno Kosei Hospital, Seki, Japan.
  • Taniguchi T; Department of Urology, Chuno Kosei Hospital, Seki, Japan.
  • Seike K; Department of Urology, Chuno Kosei Hospital, Seki, Japan.
  • Kato D; Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan.
  • Takai M; Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan.
  • Iinuma K; Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan.
  • Horie K; Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan.
  • Nakane K; Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan.
  • Koie T; Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan.
Transl Androl Urol ; 10(7): 2982-2989, 2021 Jul.
Article en En | MEDLINE | ID: mdl-34430401
BACKGROUND: This study aimed to estimate whether multiparametric magnetic resonance imaging (mpMRI)-transrectal ultrasound (TRUS) fusion biopsy (FUS-TB) increases the detection rates of clinically significant prostate cancer (csPCa) compared with TRUS-guided systematic biopsy (TRUS-GB). METHODS: This retrospective study focused on patients who underwent mpMRI before prostate biopsy (PB) with Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) scores ≥3 and prostate-specific antigen (PSA) level between 2.5 and 20 ng/mL. Before FUS-TB, the biopsy needle position was checked virtually using three-dimensional mapping. After confirming the position of the target within the prostate, biopsy needle was inserted and PB was performed. Suspicious lesions were generally targeted with 2 to 4 cores. Subsequently, 10-12 cores were biopsied for TRUS-GB. The primary endpoint was the PCa detection rate (PCDR) for patients with PCa who underwent combined FUS-TB and TRUS-GB. RESULTS: According to PI-RADS v2, 76.7% of the patients with PI-RADS v2 score ≥3 were diagnosed with PCa. The PCDRs in patients with PI-RADS v2 score of 4 or 5 were significantly higher than those in patients with PI-RADS v2 score of 3 (3 vs. 4, P<0.001; 3 vs. 5, P<0.001; 4 vs. 5, P=0.073). According to PCDR, the detection rates of PCa and csPCa in the FUS-TB were significantly higher than that in the TRUS-GB. CONCLUSIONS: Following detection of suspicious tumor lesions on mpMRI, FUS-TB use detects a higher number of PCa cases compared with TRUS-GB.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Observational_studies Idioma: En Revista: Transl Androl Urol Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: China
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Observational_studies Idioma: En Revista: Transl Androl Urol Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: China