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Unexpected lack of specialisation in the flow properties of spitting cobra venom.
Avella, Ignazio; Barajas-Ledesma, Edgar; Casewell, Nicholas R; Harrison, Robert A; Rowley, Paul D; Crittenden, Edouard; Wüster, Wolfgang; Castiglia, Riccardo; Holland, Chris; van der Meijden, Arie.
Afiliación
  • Avella I; CIBIO/InBIO - Centro de Investigação em Biodiversidade e Recursos Genéticos da Universidade do Porto,  4485-661 Vairão, Portugal.
  • Barajas-Ledesma E; Department of Materials Science and Engineering, University of Sheffield, Sheffield S1 3JD, UK.
  • Casewell NR; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
  • Harrison RA; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
  • Rowley PD; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
  • Crittenden E; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
  • Wüster W; Molecular Ecology and Fisheries Genetics Laboratory, School of Natural Sciences, Bangor University, Bangor LL57 2UW, UK.
  • Castiglia R; Dipartimento di Biologia e Biotecnologie 'Charles Darwin', Università di Roma 'La Sapienza', 00185 Rome, Italy.
  • Holland C; Department of Materials Science and Engineering, University of Sheffield, Sheffield S1 3JD, UK.
  • van der Meijden A; CIBIO/InBIO - Centro de Investigação em Biodiversidade e Recursos Genéticos da Universidade do Porto,  4485-661 Vairão, Portugal.
J Exp Biol ; 224(7)2021 04 01.
Article en En | MEDLINE | ID: mdl-34424974
Venom spitting is a defence mechanism based on airborne venom delivery used by a number of different African and Asian elapid snake species ('spitting cobras'; Naja spp. and Hemachatus spp.). Adaptations underpinning venom spitting have been studied extensively at both behavioural and morphological level in cobras, but the role of the physical properties of venom itself in its effective projection remains largely unstudied. We hereby provide the first comparative study of the physical properties of venom in spitting and non-spitting cobras. We measured the viscosity, protein concentration and pH of the venom of 13 cobra species of the genus Naja from Africa and Asia, alongside the spitting elapid Hemachatus haemachatus and the non-spitting viper Bitis arietans. By using published microCT scans, we calculated the pressure required to eject venom through the fangs of a spitting and a non-spitting cobra. Despite the differences in the modes of venom delivery, we found no significant differences between spitters and non-spitters in the rheological and physical properties of the studied venoms. Furthermore, all analysed venoms showed a Newtonian flow behaviour, in contrast to previous reports. Although our results imply that the evolution of venom spitting did not significantly affect venom viscosity, our models of fang pressure suggests that the pressure requirements to eject venom are lower in spitting cobras than in non-spitting cobras.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diente / Venenos Elapídicos Límite: Animals País/Región como asunto: Africa Idioma: En Revista: J Exp Biol Año: 2021 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diente / Venenos Elapídicos Límite: Animals País/Región como asunto: Africa Idioma: En Revista: J Exp Biol Año: 2021 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Reino Unido