The Selective 5-HT1A Agonist SR57746A Protects Intestinal Epithelial Cells and Enteric Glia Cells and Promotes Mucosal Recovery in Experimental Colitis.

Walldorf, Jens; Porzner, Marc; Neumann, Martin; Joodi, Golsa; Niess, Jan Hendrik; von Boyen, Georg; Mäder, Karsten; Weissbach, Julia; Kleger, Alexander; Seufferlein, Thomas

Walldorf, Jens; Porzner, Marc; Neumann, Martin; Joodi, Golsa; Niess, Jan Hendrik; von Boyen, Georg; Mäder, Karsten; Weissbach, Julia; Kleger, Alexander; Seufferlein, Thomas.

Afiliación

Walldorf J; Department of Internal Medicine I, Martin Luther University Halle-Wittenberg Halle (Saale), Germany.
Porzner M; Spital Lachen, Lachen, Switzerland.
Neumann M; Department of Internal Medicine I, Martin Luther University Halle-Wittenberg Halle (Saale), Germany.
Joodi G; Department of Internal Medicine I, Martin Luther University Halle-Wittenberg Halle (Saale), Germany.
Niess JH; Yale School of Medicine, New Haven, Connecticut, USA.
von Boyen G; Department of Biomedicine, University of Basel, Basel, Switzerland.
Mäder K; University Center for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital of Basel, Basel, Switzerland.
Weissbach J; Department of Internal Medicine, Hospital of Sigmaringen, Germany.
Kleger A; Institute of Pharmacy, Martin Luther University Halle-Wittenberg Halle (Saale), Germany.
Seufferlein T; Department of Internal Medicine I, Martin Luther University Halle-Wittenberg Halle (Saale), Germany.

Inflamm Bowel Dis ; 28(3): 423-433, 2022 03 02.

Article en En | MEDLINE | ID: mdl-34417821

Asunto(s)

Colitis; Agonistas del Receptor de Serotonina 5-HT1; Animales; Colitis/inducido químicamente; Colitis/tratamiento farmacológico; Colitis/metabolismo; Sulfato de Dextran/toxicidad; Modelos Animales de Enfermedad; Células Epiteliales/metabolismo; Humanos; Mucosa Intestinal/patología; Ratones; Naftalenos; Neuroglía/metabolismo; Piridinas; Agonistas del Receptor de Serotonina 5-HT1/metabolismo

Palabras clave

5HT1A; IBD; SR57746A; enteric glia; experimental colitis; serotonin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis / Agonistas del Receptor de Serotonina 5-HT1 Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Inflamm Bowel Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido

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