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Acute kidney injury during pregnancy and puerperium: an Egyptian hospital-based study.
Gaber, Tamer Z; Shemies, Rasha S; Baiomy, Azza A; Aladle, Doaa A; Mosbah, Alaa; Abdel-Hady, El Said; Sayed-Ahmed, Nagy; Sobh, Mohammed.
Afiliación
  • Gaber TZ; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt. Tamerzakigaber@hotmail.com.
  • Shemies RS; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt.
  • Baiomy AA; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt.
  • Aladle DA; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt.
  • Mosbah A; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt.
  • Abdel-Hady ES; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt.
  • Sayed-Ahmed N; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt.
  • Sobh M; Faculty of Medicine, Mansoura University, Mansoura, Dakahliya, Egypt.
J Nephrol ; 34(5): 1611-1619, 2021 10.
Article en En | MEDLINE | ID: mdl-34390480
INTRODUCTION: While acute kidney injury (AKI) in pregnancy is currently a rare entity in developed countries, it is still a common occurrence in developing countries, representing a major cause of maternal and fetal morbidity and mortality. Scarce data are published regarding pregnancy-related acute kidney injury (PRAKI) in Middle Eastern and African countries. The aim of this work is to report on the frequency, the underlying causes, and the outcomes of patients with PRAKI in an Egyptian tertiary care hospital. METHODS: This is a prospective observational study that included 40 patients representing all women who presented to the Mansoura Nephrology and Dialysis Unit with PRAKI over two years. All patients were followed up for three months after hospital discharge to assess renal outcome, and till the end of pregnancy to assess the maternal and fetal outcomes. RESULTS: PRAKI was reported  in about 1% of women who presented to the obstetrics service, and accounted for 14% of all AKI patients who presented to the renal service in our hospital. Preeclampsia (PE) and obstetric hemorrhage were the commonest causes of PRAKI. Maternal mortality occurred in 22.5% of PRAKI patients. The majority of survivors (62.5%) fully recovered, while the remaining (37.5%) individuals became dialysis dependent. Unfavorable fetal events occurred in 24 pregnancies (60%). CONCLUSION: In our hospital in Mansoura, Egypt, PRAKI represents a relevant burden with potential ominous outcomes obstetric hemorrhage and preeclampsia were the major causes. Further research is needed to understand the causes and improve the outcomes of pregnancy-related AKI.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Lesión Renal Aguda Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Female / Humans / Pregnancy País/Región como asunto: Africa Idioma: En Revista: J Nephrol Asunto de la revista: NEFROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Lesión Renal Aguda Tipo de estudio: Diagnostic_studies / Observational_studies Límite: Female / Humans / Pregnancy País/Región como asunto: Africa Idioma: En Revista: J Nephrol Asunto de la revista: NEFROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Italia