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Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma.
Scagliola, Alessandra; Miluzio, Annarita; Ventura, Gabriele; Oliveto, Stefania; Cordiglieri, Chiara; Manfrini, Nicola; Cirino, Delia; Ricciardi, Sara; Valenti, Luca; Baselli, Guido; D'Ambrosio, Roberta; Maggioni, Marco; Brina, Daniela; Bresciani, Alberto; Biffo, Stefano.
Afiliación
  • Scagliola A; Istituto Nazionale di Genetica Molecolare, INGM, "Romeo ed Enrica Invernizzi", Milan, Italy.
  • Miluzio A; Istituto Nazionale di Genetica Molecolare, INGM, "Romeo ed Enrica Invernizzi", Milan, Italy.
  • Ventura G; Department of Biosciences, University of Milan, Milan, Italy.
  • Oliveto S; Istituto Nazionale di Genetica Molecolare, INGM, "Romeo ed Enrica Invernizzi", Milan, Italy.
  • Cordiglieri C; Istituto Nazionale di Genetica Molecolare, INGM, "Romeo ed Enrica Invernizzi", Milan, Italy.
  • Manfrini N; Istituto Nazionale di Genetica Molecolare, INGM, "Romeo ed Enrica Invernizzi", Milan, Italy.
  • Cirino D; Department of Biosciences, University of Milan, Milan, Italy.
  • Ricciardi S; Department of Biosciences, University of Milan, Milan, Italy.
  • Valenti L; Istituto Nazionale di Genetica Molecolare, INGM, "Romeo ed Enrica Invernizzi", Milan, Italy.
  • Baselli G; Department of Biosciences, University of Milan, Milan, Italy.
  • D'Ambrosio R; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
  • Maggioni M; Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
  • Brina D; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
  • Bresciani A; Department of Hepatology, Fondazione IRCCS Ca' Granda Granda Ospedale Policlinico, Milan, Italy.
  • Biffo S; Department of Pathology, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Nat Commun ; 12(1): 4878, 2021 08 12.
Article en En | MEDLINE | ID: mdl-34385447
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biosíntesis de Proteínas / Factores de Iniciación de Péptidos / Carcinoma Hepatocelular / Enfermedad del Hígado Graso no Alcohólico / Neoplasias Hepáticas Tipo de estudio: Etiology_studies Límite: Animals / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biosíntesis de Proteínas / Factores de Iniciación de Péptidos / Carcinoma Hepatocelular / Enfermedad del Hígado Graso no Alcohólico / Neoplasias Hepáticas Tipo de estudio: Etiology_studies Límite: Animals / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido