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Atherosclerotic Renovascular Disease: A KDIGO (Kidney Disease: Improving Global Outcomes) Controversies Conference.
Hicks, Caitlin W; Clark, Timothy W I; Cooper, Christopher J; de Bhailís, Áine M; De Carlo, Marco; Green, Darren; Malyszko, Jolanta; Miglinas, Marius; Textor, Stephen C; Herzog, Charles A; Johansen, Kirsten L; Reinecke, Holger; Kalra, Philip A.
Afiliación
  • Hicks CW; Division of Vascular Surgery and Endovascular Therapy, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Clark TWI; Division of Interventional Radiology, Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
  • Cooper CJ; College of Medicine and Life Sciences, The University of Toledo, Toledo, OH.
  • de Bhailís ÁM; Department of Renal Medicine, Salford Royal Hospital, Salford, United Kingdom.
  • De Carlo M; Cardiothoracic and Vascular Department, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
  • Green D; Department of Renal Medicine, Salford Royal Hospital, Salford, United Kingdom.
  • Malyszko J; Department of Nephrology, Dialysis, and Internal Medicine, Warsaw Medical University, Warsaw, Poland.
  • Miglinas M; Centre of Nephrology, Vilnius University, Santaros Klinikos, Vilnius, Lithuania.
  • Textor SC; Division of Nephrology and Hypertension, Mayo Clinic, Rochester.
  • Herzog CA; Chronic Disease Research Group, Hennepin Healthcare Research Institute, University of Minnesota, Minneapolis, MN; Divisions of Cardiology, University of Minnesota, Minneapolis, MN; Hennepin Healthcare; Department of Medicine, University of Minnesota, Minneapolis, MN.
  • Johansen KL; Nephrology, University of Minnesota, Minneapolis, MN; Division of Nephrology, University of Minnesota, Minneapolis, MN.
  • Reinecke H; Department of Cardiology I: Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Münster, Münster, Germany.
  • Kalra PA; Department of Renal Medicine, Salford Royal Hospital, Salford, United Kingdom. Electronic address: philip.kalra@nca.nhs.uk.
Am J Kidney Dis ; 79(2): 289-301, 2022 02.
Article en En | MEDLINE | ID: mdl-34384806
The diagnosis and management of atherosclerotic renovascular disease (ARVD) is complex and controversial. Despite evidence from the ASTRAL (2009) and CORAL (2013) randomized controlled trials showing that percutaneous renal artery revascularization did not improve major outcomes compared with best medical therapy alone over 3-5 years, several areas of uncertainty remain. Medical therapy, including statin and antihypertensive medications, has evolved in recent years, and the use of renin-angiotensin-aldosterone system blockers is now considered the primary means to treat hypertension in the setting of ARVD. However, the criteria to identify kidneys with renal artery stenosis that have potentially salvageable function are evolving. There are also data suggesting that certain high-risk populations with specific clinical manifestations may benefit from revascularization. Here, we provide an overview of the epidemiology, diagnosis, and treatment of ARVD based on consensus recommendations from a panel of physician experts who attended the recent KDIGO (Kidney Disease: Improving Global Outcomes) Controversies Conference on central and peripheral arterial diseases in chronic kidney disease. Most focus is provided for contentious issues, and we also outline aspects of investigation and management of ARVD that require further research.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción de la Arteria Renal / Aterosclerosis / Hipertensión Renovascular Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Am J Kidney Dis Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción de la Arteria Renal / Aterosclerosis / Hipertensión Renovascular Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Am J Kidney Dis Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos