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Introns are inconsequential to efficient formation of cellular thymidine kinase mRNA in mouse L cells.
Gross, M K; Kainz, M S; Merrill, G F.
Afiliación
  • Gross MK; Department of Biochemistry and Biophysics, Oregon State University, Corvallis 97331.
Mol Cell Biol ; 7(12): 4576-81, 1987 Dec.
Article en En | MEDLINE | ID: mdl-3437897
TK mRNA levels were determined in mouse L cells transformed with intron deletion mutations of the chicken TK gene. Whether normalized per cell, per integrated gene, or per internal control signal, intron deletion did not diminish the efficiency of TK mRNA formation in transformed L cells. The results demonstrated that introns are not required for efficient biogenesis of cellular mRNA in transformed mouse L cells.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Timidina Quinasa / ARN Mensajero / Intrones Límite: Animals Idioma: En Revista: Mol Cell Biol Año: 1987 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Timidina Quinasa / ARN Mensajero / Intrones Límite: Animals Idioma: En Revista: Mol Cell Biol Año: 1987 Tipo del documento: Article Pais de publicación: Estados Unidos