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Efficacy of coronary sinus Reducer in patients with refractory angina and diabetes mellitus.
Vescovo, Giovanni M; Zivelonghi, Carlo; Agostoni, Pierfrancesco; Dekker, Mirthe; Silvis, Max; Leenders, Geert; van Kuijk, Jan Peter; Timmers, Leo; Stella, Pieter; Banai, Shmuel; Verheye, Stefan.
Afiliación
  • Vescovo GM; Interventional Cardiology, Cardiovascular Center Middelheim Hospital, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Belgium.
  • Zivelonghi C; Interventional Cardiology, Cardiovascular Center Middelheim Hospital, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Belgium.
  • Agostoni P; Interventional Cardiology, Cardiovascular Center Middelheim Hospital, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Belgium.
  • Dekker M; University Medical Center Utrecht, Utrecht, The Netherlands.
  • Silvis M; University Medical Center Utrecht, Utrecht, The Netherlands.
  • Leenders G; University Medical Center Utrecht, Utrecht, The Netherlands.
  • van Kuijk JP; Department of Cardiology, Sint Antonius Ziekenhuis, Nieuwegein, The Netherlands.
  • Timmers L; Department of Cardiology, Sint Antonius Ziekenhuis, Nieuwegein, The Netherlands.
  • Stella P; University Medical Center Utrecht, Utrecht, The Netherlands.
  • Banai S; Tel Aviv Medical Center, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel.
  • Verheye S; Interventional Cardiology, Cardiovascular Center Middelheim Hospital, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Belgium. stefan.verheye@gmail.com.
Heart Vessels ; 37(2): 194-199, 2022 Feb.
Article en En | MEDLINE | ID: mdl-34374824
Coronary sinus Reducer (CSR) implantation is currently recommended to relieve angina in patients with refractory symptoms despite optimal medical therapy and maximally achievable revascularization. The impact of diabetes mellitus on outcome after CSR implantation is at present unknown. We aimed to explore the impact of CSR in refractory angina patients with diabetes mellitus. Data from consecutive patients undergoing CSR implantation at four different centres between 2014 and 2018 were included. Patients were divided according to the presence or absence of diabetes mellitus. Primary objective of this analysis was to evaluate the clinical response to CSR implantation defined as an improvement of ≥ 1 classes of the Canadian Cardiovascular Society (CCS) Classification. A total of 219 patients were included, 116 (53%) of whom had diabetes mellitus. The median age of the population was 69 years and 167 patients (76%) were male. There were no significant differences between groups of patients with and without diabetes mellitus with respect to CCS class at baseline (p value = 0.32) and at follow-up (p = 0.75). Over a median follow-up of 393 [224-1004] days, 84 (72%) of the patients with diabetes mellitus met the primary outcome, similarly to those without diabetes mellitus (p = 0.28). Fifty-three patients (24%) did not have an improvement in CCS class and no one experienced worsening of angina. CSR implantation was equally effective in improving angina symptoms among patients with refractory angina and diabetes mellitus compared to patients without diabetes mellitus.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / Seno Coronario Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Aged / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Heart Vessels Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / Seno Coronario Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Aged / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Heart Vessels Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Japón