A metabolomics approach to investigate the proceedings of mitochondrial dysfunction in rats from prediabetes to diabetes.

Huang, Chun-Feng; Chen, Ann; Lin, Siao-Yun; Cheng, Mei-Ling; Shiao, Ming-Shi; Mao, Tso-Yen

Huang, Chun-Feng; Chen, Ann; Lin, Siao-Yun; Cheng, Mei-Ling; Shiao, Ming-Shi; Mao, Tso-Yen.

Afiliación

Huang CF; Department of Family Medicine, National Yang Ming Chiao Tung University Hospital, No.152, Xinmin Rd., Yilan City, 260 Yilan County, Taiwan, ROC.
Chen A; Department of Leisure Services Management, Chaoyang University of Technology, No.168, Jifeng E. Rd, Wufeng District, 413 Taichung City, Taiwan, ROC.
Lin SY; Department of Biomedical Sciences, Chang Gung University, No.259, Wenhua 1st Rd, Guishan Dist, 33302 Taoyuan City, Taiwan, ROC.
Cheng ML; Department of Family Medicine, National Yang Ming Chiao Tung University Hospital, No.152, Xinmin Rd., Yilan City, 260 Yilan County, Taiwan, ROC.
Shiao MS; Department of Biomedical Sciences, Chang Gung University, No.259, Wenhua 1st Rd, Guishan Dist, 33302 Taoyuan City, Taiwan, ROC.
Mao TY; Department of Biomedical Sciences, Chang Gung University, No.259, Wenhua 1st Rd, Guishan Dist, 33302 Taoyuan City, Taiwan, ROC.

Saudi J Biol Sci ; 28(8): 4762-4769, 2021 Aug.

Article en En | MEDLINE | ID: mdl-34354464

Palabras clave

CAN, acetonitrile; DM, diabetes mellitus; Diabetes; GOT, glutamate oxaloacetate transaminase; GPT, glutamate pyruvate transaminase; HF, high-fructose; HL, high-fat; HMDB, human metabolome database; KEGG, kyoto encyclopedia of genes and genomes; LC-MS, liquid chromatographymass spectrometry; Metabolic syndrome; Metabolomics; Methylation; Mitochondrial dysfunction; PCA, principal component analysis; Prediabetes; STZ, streptozotocin; TC, total cholesterol; TG, triacylglycerol; Tryptophan

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Saudi J Biol Sci Año: 2021 Tipo del documento: Article Pais de publicación: