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Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy.
Chai, Ruth Jinfen; Werner, Hendrikje; Li, Peter Yiqing; Lee, Yin Loon; Nyein, Khaing Thet; Solovei, Irina; Luu, Tuan Danh Anh; Sharma, Bhavya; Navasankari, Raju; Maric, Martina; Sim, Lois Yu En; Loh, Ying Jie; Aliwarga, Edita; Cheong, Jason Wen Long; Chojnowski, Alexandre; Autio, Matias Ilmari; Haiyang, Yu; Boon Tan, Kenneth Kian; Keng, Choong Tat; Ng, Shi Ling; Chew, Wei Leong; Ferenczi, Michael; Burke, Brian; Foo, Roger Sik Yin; Stewart, Colin L.
Afiliación
  • Chai RJ; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Werner H; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Li PY; Cardiovascular Research Institute (CVRI), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Lee YL; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Nyein KT; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Solovei I; Department of Biology II, Ludwig Maximilians University Munich, Munich, Germany.
  • Luu TDA; Cardiovascular Research Institute (CVRI), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Sharma B; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Navasankari R; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Maric M; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Sim LYE; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Loh YJ; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Aliwarga E; Cardiovascular Research Institute (CVRI), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Cheong JWL; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Chojnowski A; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Autio MI; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Haiyang Y; Muscle and Cardiac Biophysics Laboratory, Lee Kong Chien School of Medicine, Nanyang Technological University, Singapore, Singapore.
  • Boon Tan KK; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Keng CT; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Ng SL; Cardiovascular Research Institute (CVRI), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Chew WL; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Ferenczi M; Muscle and Cardiac Biophysics Laboratory, Lee Kong Chien School of Medicine, Nanyang Technological University, Singapore, Singapore.
  • Burke B; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Foo RSY; Cardiovascular Research Institute (CVRI), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. roger.foo@nus.edu.sg.
  • Stewart CL; Skin Research Institute (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. colin_stewart@SRIS.a-star.edu.sg.
Nat Commun ; 12(1): 4722, 2021 08 05.
Article en En | MEDLINE | ID: mdl-34354059
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cardiomiopatía Dilatada / Lamina Tipo A / Proteínas Asociadas a Microtúbulos Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cardiomiopatía Dilatada / Lamina Tipo A / Proteínas Asociadas a Microtúbulos Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Reino Unido