Upregulated expression of hypoxia reactive genes in peripheral blood mononuclear cells from chronic liver disease patients.

Kuwano, Akifumi; Tanaka, Masatake; Suzuki, Hideo; Kurokawa, Miho; Imoto, Koji; Tashiro, Shigeki; Goya, Takeshi; Kohjima, Motoyuki; Kato, Masaki; Ogawa, Yoshihiro

Kuwano, Akifumi; Tanaka, Masatake; Suzuki, Hideo; Kurokawa, Miho; Imoto, Koji; Tashiro, Shigeki; Goya, Takeshi; Kohjima, Motoyuki; Kato, Masaki; Ogawa, Yoshihiro.

Afiliación

Kuwano A; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Tanaka M; Department of Hepatology, Iizuka Hospital, 3-83 Yoshio-machi, Iizuka, Fukuoka, 820-8505, Japan.
Suzuki H; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Kurokawa M; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Imoto K; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Tashiro S; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Goya T; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Kohjima M; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Kato M; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Ogawa Y; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Biochem Biophys Rep ; 27: 101068, 2021 Sep.

Article en En | MEDLINE | ID: mdl-34307908

Palabras clave

AM, Adrenomedullin; ANGPTL4, Angiopoietin-like 4; Adrenomedullin; CH, chronic hepatitis; CLD, chronic liver disease; Chronic liver disease; GPx, glutathione peroxidase; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; HIF, hypoxia inducible factor; HO-1, heme oxygenase -1; HV, healthy volunteers; IL-6, Interleukin-6; Intrahepatic hypoxia; LC, liver cirrhosis; LDH, lactate dehydrogenase; MCP-1, Monocyte chemoattractant protein-1; PBMC, Peripheral blood mononuclear cells; PT, prothrombin time; Peripheral blood mononuclear cells; ROS, reactive oxygen species; SOD, Superoxide dismutase; TGF-ß, transforming growth factor-beta; TNF-α, Tumor Necrosis Factor-α; VEGF, vascular endothelial growth factor; VEGFA, vascular endothelial growth factor A; VEGFR2, vascular endothelial growth factor receptor 2

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biochem Biophys Rep Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos

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