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Factors Associated with Headache and Nausea During Magnetic Resonance-Guided Focused Ultrasound for Tremor.
Cacho-Asenjo, Elena; Honorato-Cia, Cristina; Nuñez-Cordoba, Jorge M; Fernandez-Martinez, Miguel; Gonzalez-Quarante, Lain H; Aviles-Olmos, Iciar; Gorospe, María Aranzazu; Panadero, Alfredo; Rodríguez-Oroz, María Cruz; Guridi, Jorge; Martinez-Simon, Antonio.
Afiliación
  • Cacho-Asenjo E; Department of Anesthesiology and Critical Care Clinica Universidad de Navarra Pamplona Spain.
  • Honorato-Cia C; Instituto de Investigación Sanitaria de Navarra Pamplona Spain.
  • Nuñez-Cordoba JM; Department of Anesthesiology and Critical Care Clinica Universidad de Navarra Pamplona Spain.
  • Fernandez-Martinez M; Instituto de Investigación Sanitaria de Navarra Pamplona Spain.
  • Gonzalez-Quarante LH; Research Support Service, Central Clinical Trials Unit Clinica Universidad de Navarra Pamplona Spain.
  • Aviles-Olmos I; Department of Radiology Clinica Universidad de Navarra Pamplona Spain.
  • Gorospe MA; Department of Neurosurgery Clinica Universidad de Navarra Pamplona Spain.
  • Panadero A; Department of Neurology Clinica Universidad de Navarra Pamplona Spain.
  • Rodríguez-Oroz MC; Department of Neurology Clinica Universidad de Navarra Pamplona Spain.
  • Guridi J; Department of Anesthesiology and Critical Care Clinica Universidad de Navarra Pamplona Spain.
  • Martinez-Simon A; Department of Neurology Clinica Universidad de Navarra Pamplona Spain.
Mov Disord Clin Pract ; 8(5): 701-708, 2021 Jul.
Article en En | MEDLINE | ID: mdl-34307742
BACKGROUND: During magnetic resonance-guided focused ultrasound for essential or parkinsonian tremor, adverse events (headache, nausea/vomiting, or anxiety) may alter the outcome of the procedure despite being mostly transient and mild. OBJECTIVES: Our aim was to analyze the relationship between demographic, procedural, and anesthetic characteristics with magnetic resonance/ultrasound-related events. METHODS: This was a retrospective study at the Clinica Universidad de Navarra of patients undergoing thalamotomy with magnetic resonance-guided focused ultrasound between September 2018 and October 2019. The anesthesia protocol included headache and nausea/vomiting prophylaxis and rescue therapy. Dexmedetomidine was used for anxiolysis in some patients after thorough multidisciplinary assessment. RESULTS: A total of 123 patients were included. Headache was directly related to skull density ratio (P < 0.001) and skull thickness (P = 0.02). Patients with a skull density ratio less than 0.48 had 3 times the odds of experiencing moderate or severe headache (odds ratio [OR], 3.08; 95% confidence interval [CI], 1.21-7.82) and had a higher odds of aborting sonication due to pain. Sex was associated with increased nausea (P = 0.007). Women had 4 times the odds of nausea than men (OR, 4.4; 95% CI, 1.61-12.11). Dexmedetomidine did not reduce headache or nausea incidence. Patients who received dexmedetomidine had a higher number (P = 0.01) and total minutes of sonication (P = 0.01). CONCLUSIONS: Patients with lower skull density ratios and higher skull thicknesses could benefit from an aggressive analgesic prophylaxis. Women are more likely to experience nausea. Dexmedetomidine did not reduce headache and nausea, but increased the number and duration of sonications. Its exact effect on tremor is still unclear.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline / Observational_studies / Risk_factors_studies Idioma: En Revista: Mov Disord Clin Pract Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline / Observational_studies / Risk_factors_studies Idioma: En Revista: Mov Disord Clin Pract Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos