HPIP protooncogene differentially regulates metabolic adaptation and cell fate in breast cancer cells under glucose stress via AMPK and RNF2 dependent pathways.

Penugurti, Vasudevarao; Khumukcham, Saratchandra Singh; Padala, Chiranjeevi; Dwivedi, Anju; Kamireddy, Karthik Reddy; Mukta, Srinivasulu; Bhopal, Triveni; Manavathi, Bramanandam

Penugurti, Vasudevarao; Khumukcham, Saratchandra Singh; Padala, Chiranjeevi; Dwivedi, Anju; Kamireddy, Karthik Reddy; Mukta, Srinivasulu; Bhopal, Triveni; Manavathi, Bramanandam.

Afiliación

Penugurti V; Molecular and Cellular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, 500046, Telangana, India.
Khumukcham SS; Molecular and Cellular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, 500046, Telangana, India.
Padala C; Molecular and Cellular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, 500046, Telangana, India.
Dwivedi A; Molecular and Cellular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, 500046, Telangana, India.
Kamireddy KR; Molecular and Cellular Biology Laboratory, Baylor College of Medicine, Houston, TX, United States.
Mukta S; MNJ Institute of Oncology and Regional Cancer Center, Hyderabad, 500004, Telangana, India.
Bhopal T; MNJ Institute of Oncology and Regional Cancer Center, Hyderabad, 500004, Telangana, India.
Manavathi B; Molecular and Cellular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, 500046, Telangana, India. Electronic address: manavathibsl@uohyd.ac.in.

Cancer Lett ; 518: 243-255, 2021 10 10.

Article en En | MEDLINE | ID: mdl-34302919

Asunto(s)

Proteínas Quinasas Activadas por AMP/metabolismo; Neoplasias de la Mama/metabolismo; Glucosa/metabolismo; Péptidos y Proteínas de Señalización Intracelular/metabolismo; Complejo Represivo Polycomb 1/metabolismo; Adaptación Fisiológica/fisiología; Animales; Apoptosis/fisiología; Diferenciación Celular/fisiología; Línea Celular; Línea Celular Tumoral; Femenino; Glutaminasa/metabolismo; Glutamina/metabolismo; Células HEK293; Humanos; Células MCF-7; Ratones; Ratones Desnudos; Antígenos de Histocompatibilidad Menor; Estrés Fisiológico/fisiología; Ubiquitina-Proteína Ligasas/metabolismo

Palabras clave

AMPK; Apoptosis; Cell survival; FOXO3a; Glutaminolysis; HPIP; MYC

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Péptidos y Proteínas de Señalización Intracelular / Proteínas Quinasas Activadas por AMP / Complejo Represivo Polycomb 1 / Glucosa Límite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Irlanda

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google