A Conjugation Strategy to Modulate Antigen Binding and FcRn Interaction Leads to Improved Tumor Targeting and Radioimmunotherapy Efficacy with an Antibody Targeting Prostate-Specific Antigen.

Vilhelmsson Timmermand, Oskar; Örbom, Anders; Altai, Mohamed; Zedan, Wahed; Holmqvist, Bo; Safi, Marcella; Tran, Thuy A; Strand, Sven-Erik; Strand, Joanna

Vilhelmsson Timmermand, Oskar; Örbom, Anders; Altai, Mohamed; Zedan, Wahed; Holmqvist, Bo; Safi, Marcella; Tran, Thuy A; Strand, Sven-Erik; Strand, Joanna.

Afiliación

Vilhelmsson Timmermand O; Department of Clinical Sciences Lund, Oncology, Lund University, 22243 Lund, Sweden.
Örbom A; Department of Clinical Sciences Lund, Oncology, Lund University, 22243 Lund, Sweden.
Altai M; Department of Clinical Sciences Lund, Oncology, Lund University, 22243 Lund, Sweden.
Zedan W; Department of Clinical Sciences Lund, Oncology, Lund University, 22243 Lund, Sweden.
Holmqvist B; ImaGene-iT AB, Medicon Village, 22363 Lund, Sweden.
Safi M; Department of Clinical Sciences Lund, Oncology, Lund University, 22243 Lund, Sweden.
Tran TA; Department of Radiopharmacy, Karolinska University Hospital, 17177 Stockholm, Sweden.
Strand SE; Department of Clinical Sciences Lund, Oncology, Lund University, 22243 Lund, Sweden.
Strand J; Department of Clinical Sciences Lund, Medical Radiation Physics, Lund University, 22243 Lund, Sweden.

Cancers (Basel) ; 13(14)2021 Jul 11.

Article en En | MEDLINE | ID: mdl-34298682

Palabras clave

FcRn; PSA; hu5A10; prostate cancer; radionuclide therapy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Suiza

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