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Cycloartane-type triterpenoids from the whole plants of Macrosolen bidoupensis.
Le, Kieu Hung; Huynh, Bui Linh Chi; Pham, Nguyen Kim Tuyen; Do, Thi Hong Tuoi; Nguyen, Le Thanh Tuyen; Dang, Van Son; Ngo, Quoc Luan; Tran, Thi Ngoc Mai; Bui, Trong Dat; Phan, Nhat Minh; Mai, Dinh Tri; Nguyen, Tan Phat.
Afiliación
  • Le KH; Faculty of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
  • Huynh BLC; Department of Chemistry, Le Quy Don High School for the Gifted, Ba Ria-Vung Tau Province 78000, Vietnam.
  • Pham NKT; Department of Science, Dong Nai University, Bien Hoa City, Le Quy Don, Dong Nai Province 76000, Vietnam.
  • Do THT; Faculty of Environmental Science, Sai Gon University, Ho Chi Minh City 70000, Vietnam.
  • Nguyen LTT; Department of Pharmacology, Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City 70000, Vietnam.
  • Dang VS; Saigon Pharmaceutical Sciences & Technologies Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 70000, Vietnam.
  • Ngo QL; The VNM Herbarium, Institute of Tropical Biology, Academy of Science and Technology, Ho Chi Minh City 70000, Vietnam.
  • Tran TNM; Can Tho University, Can Tho City 94000, Vietnam.
  • Bui TD; Institute of Applied Sciences, Ho Chi Minh City University of Technology, Ho Chi Minh City 700000, Vietnam.
  • Phan NM; Bioactive Compounds Laboratory, Institute of Chemical Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, Vietnam.
  • Mai DT; Faculty of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
  • Nguyen TP; Bioactive Compounds Laboratory, Institute of Chemical Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, Vietnam.
J Asian Nat Prod Res ; 24(6): 596-602, 2022 Jun.
Article en En | MEDLINE | ID: mdl-34292109
One new cycloartane-type triterpenoid, named macrobidoupoic acid A (as an C-24 epimeric mixture, 4a, 4 b), together with three known ones (1-3), were clarified by different chromatography from the M. bidoupensis whole plants. Triterpenoids (1, 3 & 4) were detected for the first time from the Macrosolen genus. Chemical structures of them were illuminated using HR-ESI-MS, and NMR (1 D & 2 D) assessments. The cytotoxic properties of triterpenoids (3 & 4) were examined against two human cancer cell lines (A549, and RD) by MTT assay. As results shown, triterpenoids (3 & 4) possessed moderate cytotoxic activity against A549 and RD cancer cells (IC50 ranged from 5.44 to 39.52 µM).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triterpenos Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triterpenos Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido