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Gender Difference in the Relationships between Inflammatory Markers, Serum Uric Acid and Framingham Risk Score.
Huang, Jui-Hua; Li, Ren-Hau; Huang, Shu-Ling; Sia, Hon-Ke; Yu, Chao-Hung; Tang, Feng-Cheng.
Afiliación
  • Huang JH; Department of Golden-Ager Industry Management, Chaoyang University of Technology, Taichung 413, Taiwan.
  • Li RH; Occupational Health Center, Changhua Christian Hospital, Changhua 500, Taiwan.
  • Huang SL; Department of Psychology, Chung Shan Medical University, Taichung 402, Taiwan.
  • Sia HK; Department of Psychology, Chung Shan Medical University, Taichung 402, Taiwan.
  • Yu CH; Room of Clinical Psychology, Chung Shan Medical University Hospital, Taichung 402, Taiwan.
  • Tang FC; Division of Endocrinology and Metabolism, Changhua Christian Hospital, Changhua 500, Taiwan.
Article en En | MEDLINE | ID: mdl-34281041
The purpose of the present study was to explore the role of gender in the relation of high-sensitivity C-reactive protein (hsCRP), white blood cell (WBC) count, and serum uric acid (UA) to the risk of future cardiovascular disease (CVD) events. In total, 404 workers were recruited to obtain the measurements of serum markers for CVD risk. Demographic data, nutrition, exercise, smoking, and alcohol consumption were assessed through a questionnaire. The Framingham Risk Score (FRS) was adopted to estimate the risk of future CVD events. Multiple linear regression models were used to determine CVD risk markers in relation to the FRS by gender. The hsCRP was not significantly correlated with the FRS for all workers after adjusting for covariates, including demographic data and health-related lifestyle. WBC count was positively correlated with FRS for all workers, but WBC count did not show an interaction with gender with respect to the FRS. Serum UA showed an interaction with gender on the FRS, and UA positively correlated with the FRS in males though not in females. With respect to CVD prevention, the WBC count can be used to monitor the risk for all workers. Due to a gender difference shown in the relationship between serum UA and the FRS, serum UA can be a monitor of the risk of future CVD events in male workers only.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Úrico / Enfermedades Cardiovasculares Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Female / Humans / Male Idioma: En Revista: Int J Environ Res Public Health Año: 2021 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Úrico / Enfermedades Cardiovasculares Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Female / Humans / Male Idioma: En Revista: Int J Environ Res Public Health Año: 2021 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Suiza