Anti-CD47 antibody administration via cisterna magna in proper dosage can reduce perihematomal cell death following intracerebral hemorrhage in rats.

Song, Yan; Wang, Huaqing; Li, Feng; Huang, Qibing; Zhang, Zeli

Song, Yan; Wang, Huaqing; Li, Feng; Huang, Qibing; Zhang, Zeli.

Afiliación

Song Y; Department of Emergency Neurosurgical Intensive Care Unit, Qilu Hospital of Shandong University and Brain Science Research Institute of Shandong University, Jinan, Shandong Province, 250012, PR China. Electronic address: supersy326@163.com.
Wang H; Department of Emergency Neurosurgical Intensive Care Unit, Qilu Hospital of Shandong University and Brain Science Research Institute of Shandong University, Jinan, Shandong Province, 250012, PR China. Electronic address: 13791036664@163.com.
Li F; Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute of Shandong University, Jinan, Shandong Province, 250012, PR China. Electronic address: 18560083120@163.com.
Huang Q; Department of Emergency Neurosurgical Intensive Care Unit, Qilu Hospital of Shandong University and Brain Science Research Institute of Shandong University, Jinan, Shandong Province, 250012, PR China. Electronic address: sdhqbing@163.com.
Zhang Z; Department of Emergency Neurosurgical Intensive Care Unit, Qilu Hospital of Shandong University and Brain Science Research Institute of Shandong University, Jinan, Shandong Province, 250012, PR China. Electronic address: tylor1216@163.com.

Brain Res Bull ; 174: 359-365, 2021 09.

Article en En | MEDLINE | ID: mdl-34252444

Asunto(s)

Anticuerpos Bloqueadores/uso terapéutico; Antígeno CD47/inmunología; Muerte Celular/efectos de los fármacos; Hemorragia Cerebral Traumática/tratamiento farmacológico; Hemorragia Cerebral/tratamiento farmacológico; Cisterna Magna; Animales; Anticuerpos Bloqueadores/administración & dosificación; Antígenos CD/biosíntesis; Antígenos de Diferenciación Mielomonocítica/biosíntesis; Ganglios Basales/patología; Caspasa 3/metabolismo; Relación Dosis-Respuesta a Droga; Hematoma; Masculino; Microinyecciones; Proteínas Proto-Oncogénicas c-bcl-2/biosíntesis; Ratas; Ratas Wistar

Palabras clave

Anti-CD47 antibody; CD 47; Cell death; Cisterna magna; Intracerebral hemorrhage; Phagocytosis

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemorragia Cerebral / Cisterna Magna / Muerte Celular / Anticuerpos Bloqueadores / Hemorragia Cerebral Traumática / Antígeno CD47 Límite: Animals Idioma: En Revista: Brain Res Bull Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google