Effect of Malt-PEG-Abz@RSL3 micelles on HepG2 cells based on NADPH depletion and GPX4 inhibition in ferroptosis.

Li, Wenhua; Liu, Xiaoying; Cheng, Xu; Zhang, Wenyuan; Gong, Chen; Gao, Chuya; Peng, Haisheng; Yang, Bo; Tang, Shukun; Tao, Haiquan

Li, Wenhua; Liu, Xiaoying; Cheng, Xu; Zhang, Wenyuan; Gong, Chen; Gao, Chuya; Peng, Haisheng; Yang, Bo; Tang, Shukun; Tao, Haiquan.

Afiliación

Li W; School of Pharmacy, Harbin University of Commerce, Harbin, China.
Liu X; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.
Cheng X; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.
Zhang W; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.
Gong C; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.
Gao C; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.
Peng H; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.
Yang B; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.
Tang S; School of Pharmacy, Harbin University of Commerce, Harbin, China.
Tao H; Department of Pharmaceutics, Daqing Campus of Harbin Medical University, Daqing, China.

J Drug Target ; 30(2): 208-218, 2022 02.

Article en En | MEDLINE | ID: mdl-34236257

Asunto(s)

Ferroptosis; Carbolinas; Células Hep G2; Humanos; Micelas; NADP

Palabras clave

Ferroptosis; GPX4 inhibition; HepG2 cells; NADPH depletion; micelles

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ferroptosis Límite: Humans Idioma: En Revista: J Drug Target Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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