Your browser doesn't support javascript.
loading
Long-Term Application of Cerebellar Transcranial Direct Current Stimulation Does Not Improve Motor Learning in Parkinson's Disease.
de Albuquerque, Lidio Lima; Pantovic, Milan; Clingo, Mitchell G; Fischer, Katherine M; Jalene, Sharon; Landers, Merrill R; Mari, Zoltan; Poston, Brach.
Afiliación
  • de Albuquerque LL; School of Health and Applied Human Sciences, University of North Carolina at Wilmington, Wilmington, NC, USA.
  • Pantovic M; Department of Kinesiology and Nutrition Sciences, University of Nevada Las Vegas, Las Vegas, NV, USA.
  • Clingo MG; School of Medicine, University of Nevada Las Vegas, Las Vegas, NV, USA.
  • Fischer KM; Department of Kinesiology and Nutrition Sciences, University of Nevada Las Vegas, Las Vegas, NV, USA.
  • Jalene S; Department of Kinesiology and Nutrition Sciences, University of Nevada Las Vegas, Las Vegas, NV, USA.
  • Landers MR; Department of Physical Therapy, University of Nevada Las Vegas, Las Vegas, NV, USA.
  • Mari Z; Movement Disorders Program, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
  • Poston B; Department of Kinesiology and Nutrition Sciences, University of Nevada Las Vegas, Las Vegas, NV, USA. brach.poston@unlv.edu.
Cerebellum ; 21(3): 333-349, 2022 Jun.
Article en En | MEDLINE | ID: mdl-34232470
Cerebellar transcranial direct current stimulation (c-tDCS) enhances motor skill acquisition and motor learning in young and old adults. Since the cerebellum is involved in the pathophysiology of Parkinson's disease (PD), c-tDCS may represent an intervention with potential to improve motor learning in PD. The primary purpose was to determine the influence of long-term application of c-tDCS on motor learning in PD. The secondary purpose was to examine the influence of long-term application of c-tDCS on transfer of motor learning in PD. The study was a randomized, double-blind, SHAM-controlled, between-subjects design. Twenty-one participants with PD were allocated to either a tDCS group or a SHAM stimulation group. Participants completed 9 practice sessions over a 2-week period that involved extensive practice of an isometric pinch grip task (PGT) and a rapid arm movement task (AMT). These practice tasks were performed over a 25-min period concurrent with either anodal c-tDCS or SHAM stimulation. A set of transfer tasks that included clinical rating scales, manual dexterity tests, and lower extremity assessments were quantified in Test sessions at Baseline, 1, 14, and 28 days after the end of practice (EOP). There were no significant differences between the c-tDCS and SHAM groups as indicated by performance changes in the practice and transfer tasks from Baseline to the 3 EOP Tests. The findings indicate that long-term application of c-tDCS does not improve motor learning or transfer of motor learning to a greater extent than practice alone in PD.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Estimulación Transcraneal de Corriente Directa Tipo de estudio: Clinical_trials / Guideline Límite: Adult / Humans Idioma: En Revista: Cerebellum Asunto de la revista: CEREBRO Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Estimulación Transcraneal de Corriente Directa Tipo de estudio: Clinical_trials / Guideline Límite: Adult / Humans Idioma: En Revista: Cerebellum Asunto de la revista: CEREBRO Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos