Your browser doesn't support javascript.
loading
Indolent CD8+ primary cutaneous T-cell lymphoma involving the eyelid of an adolescent.
Minzenmayer, Andrew N; Taylor, Kirby; Housewright, Chad D; Bicknell, Lindsay M; Hendrick, Sophia J; Tsai, Jonathan H; Siref, Andrew.
Afiliación
  • Minzenmayer AN; Department of Dermatology, Baylor Scott and White Central Texas, Temple, Texas, USA.
  • Taylor K; Department of Ophthalmology, Baylor Scott and White Central Texas, Temple, Texas, USA.
  • Housewright CD; Department of Dermatology, Baylor Scott and White Central Texas, Temple, Texas, USA.
  • Bicknell LM; Department of Dermatology, Baylor Scott and White Central Texas, Temple, Texas, USA.
  • Hendrick SJ; Department of Dermatology, Baylor Scott and White Central Texas, Temple, Texas, USA.
  • Tsai JH; Department of Ophthalmology, Baylor Scott and White Central Texas, Temple, Texas, USA.
  • Siref A; Department of Pathology, Baylor Scott and White Central Texas, Temple, Texas, USA.
J Cutan Pathol ; 48(12): 1489-1492, 2021 Dec.
Article en En | MEDLINE | ID: mdl-34218462
Primary cutaneous acral CD8+ T-cell lymphoma (PCACTL) is currently a provisional entity defined as a rare cutaneous proliferation of atypical CD8+ lymphocytes that preferentially involves acral sites and has a good prognosis. We present a case of primary cutaneous CD8+ T-cell lymphoma involving the eyelid of an adolescent male. The case shares features with PCACTL, including indolent clinical behavior and expression of CD68 in a Golgi-associated dot-like pattern; however, other features differ significantly from PCACTL as currently defined by the World Health Organization (WHO). These features include ulceration, expression of CD56, granzyme B, and perforin, and a high proliferative index. Given these discrepancies, our case is currently best classified as a CD8+ primary cutaneous peripheral T-cell lymphoma, not otherwise specified. We review the differential diagnosis for this case and suggest expanding the definition of PCACTL.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Linfoma Cutáneo de Células T / Linfocitos T CD8-positivos / Neoplasias de los Párpados Tipo de estudio: Prognostic_studies Límite: Adolescent / Humans / Male Idioma: En Revista: J Cutan Pathol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Linfoma Cutáneo de Células T / Linfocitos T CD8-positivos / Neoplasias de los Párpados Tipo de estudio: Prognostic_studies Límite: Adolescent / Humans / Male Idioma: En Revista: J Cutan Pathol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos