The role of endocannabinoid pathway in the neuropathology of Alzheimer's disease: Can the inhibitors of MAGL and FAAH prove to be potential therapeutic targets against the cognitive impairment associated with Alzheimer's disease?

Bajaj, Shivanshu; Jain, Shreshta; Vyas, Preeti; Bawa, Sandhya; Vohora, Divya

Bajaj, Shivanshu; Jain, Shreshta; Vyas, Preeti; Bawa, Sandhya; Vohora, Divya.

Afiliación

Bajaj S; Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Jain S; Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Vyas P; Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Bawa S; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Vohora D; Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. Electronic address: dvohra@jamiahamdard.ac.in.

Brain Res Bull ; 174: 305-322, 2021 09.

Article en En | MEDLINE | ID: mdl-34217798

Asunto(s)

Enfermedad de Alzheimer/tratamiento farmacológico; Amidohidrolasas/antagonistas & inhibidores; Trastornos del Conocimiento/tratamiento farmacológico; Endocannabinoides; Monoacilglicerol Lipasas/antagonistas & inhibidores; Transducción de Señal/efectos de los fármacos; Enfermedad de Alzheimer/fisiopatología; Enfermedad de Alzheimer/psicología; Animales; Moduladores de Receptores de Cannabinoides; Trastornos del Conocimiento/etiología; Humanos

Palabras clave

Alzheimer's disease; Anandamide (AEA); Cognitive decline; Endocannabinoids; Fatty acid amide hydrolase (FAAH); Monoacylglycerol lipase (MAGL)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Trastornos del Conocimiento / Endocannabinoides / Enfermedad de Alzheimer / Amidohidrolasas / Monoacilglicerol Lipasas Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Brain Res Bull Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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