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Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.
He, Chen; Xu, Ke; Zhu, Xiaoyan; Dunphy, Paige S; Gudenas, Brian; Lin, Wenwei; Twarog, Nathaniel; Hover, Laura D; Kwon, Chang-Hyuk; Kasper, Lawryn H; Zhang, Junyuan; Li, Xiaoyu; Dalton, James; Jonchere, Barbara; Mercer, Kimberly S; Currier, Duane G; Caufield, William; Wang, Yingzhe; Xie, Jia; Broniscer, Alberto; Wetmore, Cynthia; Upadhyaya, Santhosh A; Qaddoumi, Ibrahim; Klimo, Paul; Boop, Frederick; Gajjar, Amar; Zhang, Jinghui; Orr, Brent A; Robinson, Giles W; Monje, Michelle; Freeman Iii, Burgess B; Roussel, Martine F; Northcott, Paul A; Chen, Taosheng; Rankovic, Zoran; Wu, Gang; Chiang, Jason; Tinkle, Christopher L; Shelat, Anang A; Baker, Suzanne J.
Afiliación
  • He C; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Xu K; Center for Applied Bioinformatics, Memphis, TN, USA.
  • Zhu X; Department of Computational Biology, Memphis, TN, USA.
  • Dunphy PS; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Gudenas B; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Lin W; Department of Oncology, Memphis, TN, USA.
  • Twarog N; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Hover LD; Department of Chemical Biology and Therapeutics, Memphis, TN, USA.
  • Kwon CH; Department of Chemical Biology and Therapeutics, Memphis, TN, USA.
  • Kasper LH; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Zhang J; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Li X; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Dalton J; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Jonchere B; Department of Pathology, Memphis, TN, USA.
  • Mercer KS; Department of Pathology, Memphis, TN, USA.
  • Currier DG; Department of Tumor Cell Biology, Memphis, TN, USA.
  • Caufield W; Department of Tumor Cell Biology, Memphis, TN, USA.
  • Wang Y; Department of Chemical Biology and Therapeutics, Memphis, TN, USA.
  • Xie J; Preclinical Pharmacokinetics Shared Resource St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Broniscer A; Preclinical Pharmacokinetics Shared Resource St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Wetmore C; Department of Chemical Biology and Therapeutics, Memphis, TN, USA.
  • Upadhyaya SA; Division of Hematology-Oncology, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
  • Qaddoumi I; Exelixis, Inc., Alameda, CA, USA.
  • Klimo P; Department of Oncology, Memphis, TN, USA.
  • Boop F; Department of Oncology, Memphis, TN, USA.
  • Gajjar A; Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Zhang J; Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Orr BA; Department of Oncology, Memphis, TN, USA.
  • Robinson GW; Department of Computational Biology, Memphis, TN, USA.
  • Monje M; Department of Pathology, Memphis, TN, USA.
  • Freeman Iii BB; Department of Oncology, Memphis, TN, USA.
  • Roussel MF; Department of Neurology, Stanford University, Stanford, CA, USA.
  • Northcott PA; Preclinical Pharmacokinetics Shared Resource St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Chen T; Department of Tumor Cell Biology, Memphis, TN, USA.
  • Rankovic Z; Department of Developmental Neurobiology, Memphis, TN, USA.
  • Wu G; Department of Chemical Biology and Therapeutics, Memphis, TN, USA.
  • Chiang J; Department of Chemical Biology and Therapeutics, Memphis, TN, USA.
  • Tinkle CL; Center for Applied Bioinformatics, Memphis, TN, USA.
  • Shelat AA; Department of Computational Biology, Memphis, TN, USA.
  • Baker SJ; Department of Pathology, Memphis, TN, USA. Suzanne.Baker@StJude.org.
Nat Commun ; 12(1): 4089, 2021 07 02.
Article en En | MEDLINE | ID: mdl-34215733
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heterogeneidad Genética / Glioma Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heterogeneidad Genética / Glioma Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido