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Abnormal Levels of Pepsinogen I and Gastrin 17 in a case of Ménétrier Disease.
Crafa, Pellegrino; Franceschi, Marilisa; Franzoni, Lorella; Di Mario, Francesco.
Afiliación
  • Crafa P; Department of Medicine and Surgery, University of Parma. pellegrino.crafa@unipr.it.
  • Franceschi M; Department of Medicine, ULSS7 Pedemontana, Hospital AltoVicentino, Santorso (VI). marilisa.franceschi@aulss7.veneto.it.
  • Franzoni L; Department of Medicine and Surgery, University of Parma. lorella.franzoni@unipr.it.
  • Di Mario F; Department of Medicine and Surgery, University of Parma. francesco.dimario@unipr.it.
Acta Biomed ; 92(3): e2021207, 2021 07 01.
Article en En | MEDLINE | ID: mdl-34212902
BACKGROUND AND AIM: We describe a case of Ménétrier disease, occurred in female patient. METHODS: We decide to assess by non-invasive way (serum pepsinogens and gastrin 17) the secretory status of gastric mucosa, to confirm previous data of the literature, claiming high levels of both acid secretion and hypergastrinemia in this rare pathological condition. RESULTS AND CONCLUSION: We find in the subject the highest values of pepsinogen 1 - a marker of acid secretion - never described in the literature to our knowledge: 1940 mcg/L, being normal values ranging from 30-160 mcg/L. Similarly, gastrin 17, produced 90% in the antrum and responsible for negative acid feedback, was very high: 139 pg/L, ranging normal values between 1-10 pg/L. (www.actabiomedica.it).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pepsinógeno A / Gastritis Hipertrófica Límite: Female / Humans Idioma: En Revista: Acta Biomed Asunto de la revista: MEDICINA Año: 2021 Tipo del documento: Article Pais de publicación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pepsinógeno A / Gastritis Hipertrófica Límite: Female / Humans Idioma: En Revista: Acta Biomed Asunto de la revista: MEDICINA Año: 2021 Tipo del documento: Article Pais de publicación: Italia