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Precipitation at Room Temperature as a Fast and Versatile Method for Calcium Phosphate/TiO2 Nanocomposites Synthesis.
Erceg, Ina; Selmani, Atida; Gajovic, Andreja; Radatovic, Borna; Segota, Suzana; Curlin, Marija; Strasser, Vida; Kontrec, Jasminka; Kralj, Damir; Maltar-Strmecki, Nadica; Barbir, Rinea; Pem, Barbara; Vinkovic Vrcek, Ivana; Dutour Sikiric, Maja.
Afiliación
  • Erceg I; Laboratory for Biocolloids and Surface Chemistry, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Selmani A; Laboratory for Biocolloids and Surface Chemistry, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Gajovic A; Laboratory for Energy Conversion Materials and Sensors, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Radatovic B; Institute of Physics, Bijenicka Cesta 46, 10000 Zagreb, Croatia.
  • Segota S; Laboratory for Biocolloids and Surface Chemistry, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Curlin M; Department of Histology and Embryology, School of Medicine, University of Zagreb, Salata 3, 10000 Zagreb, Croatia.
  • Strasser V; Laboratory for Biocolloids and Surface Chemistry, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Kontrec J; Laboratory for Precipitation Processes, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Kralj D; Laboratory for Precipitation Processes, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Maltar-Strmecki N; Laboratory for Magnetic Resonances, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
  • Barbir R; Institute for Medical Research and Occupational Health, Ksaverska Cesta 2, 10000 Zagreb, Croatia.
  • Pem B; Institute for Medical Research and Occupational Health, Ksaverska Cesta 2, 10000 Zagreb, Croatia.
  • Vinkovic Vrcek I; Institute for Medical Research and Occupational Health, Ksaverska Cesta 2, 10000 Zagreb, Croatia.
  • Dutour Sikiric M; Laboratory for Biocolloids and Surface Chemistry, Ruder Boskovic Institute, Bijenicka Cesta 54, 10000 Zagreb, Croatia.
Nanomaterials (Basel) ; 11(6)2021 Jun 09.
Article en En | MEDLINE | ID: mdl-34207588
The constantly growing need for advanced bone regeneration materials has motivated the development of calcium phosphates (CaPs) composites with a different metal or metal-oxide nanomaterials and their economical and environmentally friendly production. Here, two procedures for the synthesis of CaPs composites with TiO2 nanoplates (TiNPl) and nanowires (TiNWs) were tested, with the immersion of TiO2 nanomaterials (TiNMs) in corrected simulated body fluid (c-SBF) and precipitation of CaP in the presence of TiNMs. The materials obtained were analyzed by powder X-ray diffraction, spectroscopic and microscopic techniques, Brunauer-Emmett-Teller surface area analysis, thermogravimetric analysis, dynamic and electrophoretic light scattering, and their hemocompatibility and ability to induce reactive oxygen species were evaluated. After 28 days of immersion in c-SBF, no significant CaP coating was formed on TiNMs. However, the composites with calcium-deficient apatite (CaDHA) were obtained after one hour in the spontaneous precipitation system. In the absence of TiNMs, CaDHA was also formed, indicating that control of the CaP phase formed can be accomplished by fine-tuning conditions in the precipitation system. Although the morphology and size of crystalline domains of CaDHA obtained on the different nanomaterials differed, no significant difference was detected in their local structure. Composites showed low reactive oxygen species (ROS) production and did not induce hemolysis. The results obtained indicate that precipitation is a suitable and fast method for the preparation of CaPs/TiNMs nanocomposites which shows great potential for biomedical applications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanomaterials (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanomaterials (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Suiza