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Confocal Microscopy and Anterior Segment Optical Coherence Tomography Imaging of the Ocular Surface and Bleb Morphology in Medically and Surgically Treated Glaucoma Patients: A Review.
Carnevale, Carmela; Riva, Ivano; Roberti, Gloria; Michelessi, Manuele; Tanga, Lucia; Verticchio Vercellin, Alice C; Agnifili, Luca; Manni, Gianluca; Harris, Alon; Quaranta, Luciano; Oddone, Francesco.
Afiliación
  • Carnevale C; IRCCS-Fondazione Bietti, Rome, Via Livenza, 3, 00198 Rome, Italy.
  • Riva I; Department of Surgical & Clinical, Diagnostic and Pediatric Sciences, Section of Ophthalmology, University of Pavia-IRCCS Fondazione Policlinico San Matteo, 27100 Pavia, Italy.
  • Roberti G; IRCCS-Fondazione Bietti, Rome, Via Livenza, 3, 00198 Rome, Italy.
  • Michelessi M; IRCCS-Fondazione Bietti, Rome, Via Livenza, 3, 00198 Rome, Italy.
  • Tanga L; IRCCS-Fondazione Bietti, Rome, Via Livenza, 3, 00198 Rome, Italy.
  • Verticchio Vercellin AC; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.
  • Agnifili L; Ophthalmology Clinic, Department of Medicine and Aging Science, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
  • Manni G; IRCCS-Fondazione Bietti, Rome, Via Livenza, 3, 00198 Rome, Italy.
  • Harris A; Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.
  • Quaranta L; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA.
  • Oddone F; Department of Surgical & Clinical, Diagnostic and Pediatric Sciences, Section of Ophthalmology, University of Pavia-IRCCS Fondazione Policlinico San Matteo, 27100 Pavia, Italy.
Pharmaceuticals (Basel) ; 14(6)2021 Jun 18.
Article en En | MEDLINE | ID: mdl-34207162
Glaucoma patients often suffer from ocular surface disease (OSD) caused by the chronic administration of topical anti-glaucoma medications, especially in cases of long-term therapy with preserved or multiple drugs. Additionally, glaucoma surgery may determine ocular surface changes related to the formation and location of the filtering bleb, the application of anti-mitotic agents, and the post-operative wound-healing processes within the conjunctiva. Recently, several studies have evaluated the role of advanced diagnostic imaging technologies such as in vivo confocal microscopy (IVCM) and anterior segment-optical coherence tomography (AS-OCT) in detecting microscopic and macroscopic features of glaucoma therapy-related OSD. Their clinical applications are still being explored, with recent particular attention paid to analyzing the effects of new drug formulations and of minimally invasive surgical procedures on the ocular surface status. In this review, we summarize the current knowledge about the main changes of the ocular surface identified at IVCM and AS-OCT in glaucoma patients under medical therapy, or after surgical treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza