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Systematic Review and Meta-Analysis of the Effectiveness of Calcium-Phosphate Coating on the Osseointegration of Titanium Implants.
López-Valverde, Nansi; López-Valverde, Antonio; Aragoneses, Juan Manuel; Macedo de Sousa, Bruno; Rodrigues, María João; Ramírez, Juan Manuel.
Afiliación
  • López-Valverde N; Department of Surgery, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, 37007 Salamanca, Spain.
  • López-Valverde A; Department of Surgery, Instituto de Investigación Biomédica de Salamanca (IBSAL), University of Salamanca, 37007 Salamanca, Spain.
  • Aragoneses JM; Faculty of Dentistry, Universidad Alfonso X El Sabio, 28691 Madrid, Spain.
  • Macedo de Sousa B; Polo I-Edifício Central Rua Larga, Institute for Occlusion and Orofacial Pain Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
  • Rodrigues MJ; Polo I-Edifício Central Rua Larga, Institute for Occlusion and Orofacial Pain Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
  • Ramírez JM; Department of Morphological Sciences, University of Cordoba, Avenida Menéndez Pidal S/N, 14071 Cordoba, Spain.
Materials (Basel) ; 14(11)2021 Jun 02.
Article en En | MEDLINE | ID: mdl-34199366
Ca-P coatings on Ti implants have demonstrated good osseointegration capability due to their similarity to bone mineral matter. Three databases (PubMed, Embase, and Web of Science) were searched electronically in February 2021 for preclinical studies in unmodified experimental animals, with at least four weeks of follow-up, measuring bone-to-implant contact (BIC). Although 107 studies were found in the initial search, only eight experimental preclinical studies were included. Adverse events were selected by two independent investigators. The risk of bias assessment of the selected studies was evaluated using the Cochrane Collaboration Tool. Finally, a meta-analysis of the results found no statistical significance between implants coated with Ca-P and implants with etched conventional surfaces (difference of means, random effects: 5.40; 99% CI: -5.85, 16.65). With the limitations of the present review, Ca-P-coated Ti surfaces have similar osseointegration performance to conventional etched surfaces. Future well-designed studies with large samples are required to confirm our findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Materials (Basel) Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Materials (Basel) Año: 2021 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza