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Hypertension and hypertension severity in Hispanics/Latinx with MS.
Robers, Michael V; Chan, Chan; Vajdi, Borna; Chiong-Rivero, Horacio; Martinez, Andrea; Burnett, Margaret E; Ramanathan, Murali; Amezcua, Lilyana.
Afiliación
  • Robers MV; Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA/Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA.
  • Chan C; Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
  • Vajdi B; Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
  • Chiong-Rivero H; Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
  • Martinez A; Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
  • Burnett ME; Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
  • Ramanathan M; Departments of Pharmaceutical Sciences and Neurology, State University of New York, Buffalo, NY, USA.
  • Amezcua L; Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
Mult Scler ; 27(12): 1894-1901, 2021 10.
Article en En | MEDLINE | ID: mdl-34197237
BACKGROUND: Vascular comorbidities (VCs) including hypertension (HTN) are associated with worse multiple sclerosis (MS) outcomes. HTN is common in Latinx, but the prevalence and relationship with disability are unknown in Latinx with MS. METHODS: Latinx (n = 451) from the Alliance for Research in Hispanic MS (ARHMS) seen between 2007 and 2019 were included. HTN, diabetes (DM), hyperlipidemia (HLD), ischemic events, and smoking were considered VC. Blood pressures (BPs) were classified using the American Heart Association (AHA) criteria. Logistic regression determined associations between VC and ambulatory disability accounting for age, sex, and disease duration. RESULTS: Medical comorbidities were found in 41.9% and VC in 24.2%. Smoking (13.6%) and HTN (7.3%) were the most common. HTN was the most common over the age of 40 (12.6%). The odds of having severe disability were three times higher for those with HTN (odds ratio [OR], 3.12; 95% confidence interval (CI), 1.37-7.12). Stage II HTN according to AHA also tripled the odds (OR, 2.89; 95%CI, 1.11-7.55). AHA BP confirmed HTN in 27.5% (compared to 7.3% with established diagnosis). CONCLUSION: HTN diagnosis and stage II HTN defined by AHA were independently associated with severe ambulatory disability in Latinx with MS. HTN was underdiagnosed. Future studies should assess whether HTN treatment control would prevent disability in MS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipertensión / Esclerosis Múltiple Tipo de estudio: Etiology_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Mult Scler Asunto de la revista: NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipertensión / Esclerosis Múltiple Tipo de estudio: Etiology_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Mult Scler Asunto de la revista: NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido