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Household air pollution, ultrasound measurement, fetal biometric parameters and intrauterine growth restriction.
Dutta, Anindita; Alexander, Donee; Karrison, Theodore; Morhasson-Bello, Oludare; Wilson, Nathaniel; Atalabi, Omolola Mojisola; Adu, Damilola; Ibigbami, Tope; Adekunle, Samuel; Adepoju, Dayo; Olamijulo, John; Akinwunmi, Omolola; Afolabi, Oluniyi S; Deji-Abiodun, Oluwafunmilade; Adedokun, Babatunde; Aschebrook-Kilfoy, Briseis; Ojengbede, Oladosu; Olopade, Christopher O.
Afiliación
  • Dutta A; Department of Medicine and Center for Global Health, University of Chicago, Chicago, USA.
  • Alexander D; Department of Medicine and Center for Global Health, University of Chicago, Chicago, USA.
  • Karrison T; Department of Public Health Sciences, University of Chicago, Chicago, USA.
  • Morhasson-Bello O; Department of Obstetrics and Gynecology, University of Ibadan, Ibadan, Nigeria.
  • Wilson N; Pritzker School of Medicine, University of Chicago, Chicago, USA.
  • Atalabi OM; Department of Radiology, University of Ibadan, Ibadan, Nigeria.
  • Adu D; Healthy Life for All Foundation, House 38, University College Hospital, Ibadan, Nigeria.
  • Ibigbami T; Healthy Life for All Foundation, House 38, University College Hospital, Ibadan, Nigeria.
  • Adekunle S; Healthy Life for All Foundation, House 38, University College Hospital, Ibadan, Nigeria.
  • Adepoju D; Healthy Life for All Foundation, House 38, University College Hospital, Ibadan, Nigeria.
  • Olamijulo J; Healthy Life for All Foundation, House 38, University College Hospital, Ibadan, Nigeria.
  • Akinwunmi O; Department of Radiology, University of Ibadan, Ibadan, Nigeria.
  • Afolabi OS; Department of Radiology, University of Ibadan, Ibadan, Nigeria.
  • Deji-Abiodun O; Department of Medicine and Center for Global Health, University of Chicago, Chicago, USA.
  • Adedokun B; Department of Medicine and Center for Global Health, University of Chicago, Chicago, USA.
  • Aschebrook-Kilfoy B; Department of Public Health Sciences, University of Chicago, Chicago, USA.
  • Ojengbede O; Department of Obstetrics and Gynecology, University of Ibadan, Ibadan, Nigeria.
  • Olopade CO; Department of Medicine and Center for Global Health, University of Chicago, Chicago, USA. solopade@bsd.uchicago.edu.
Environ Health ; 20(1): 74, 2021 06 23.
Article en En | MEDLINE | ID: mdl-34187482
BACKGROUND: Low birthweight, intrauterine growth restriction (IUGR) and perinatal mortality have been associated with air pollution. However, intervention studies that use ultrasound measurements to assess the effects of household air pollution (HAP) on fetal biometric parameters (FBP) are rare. We investigated the effect of a cookstove intervention on FBP and IUGR in a randomized controlled trial (RCT) cohort of HAP-exposed pregnant Nigerian women. METHODS: We recruited 324 women early in the second trimester of pregnancy. Between 16 and 18 weeks, we randomized them to either continue cooking with firewood/kerosene (control group) or receive a CleanCook stove and ethanol fuel (intervention group). We measured fetal biparietal diameter (BPD), head circumference (HC), femur length (FL), abdominal circumference (AC) and ultrasound-estimated fetal weight (U-EFW) in the second and third trimesters. The women were clinically followed up at six regular time points during their pregnancies. Once during the women's second trimester and once during the third, we made 72-h continuous measurements of their personal exposures to particulate matter having aerodynamic diameter < 2.5 µm (PM2.5). We adopted a modified intent-to-treat approach for the analysis. Differences between the intervention and control groups on impact of HAP on fetal growth trajectories were analyzed using mixed effects regression models. RESULTS: There were no significant differences in fetal growth trajectories between the intervention and control groups. CONCLUSIONS: Larger studies in a setting of low ambient air pollution are required to further investigate the effect of transitioning to a cleaner fuel such as ethanol on intrauterine growth. TRIAL REGISTRATION: ClinicalTrials.gov NCT02394574 ; September 2012.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación del Aire Interior / Culinaria / Desarrollo Fetal / Contaminantes Atmosféricos / Material Particulado Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adolescent / Adult / Female / Humans / Pregnancy País/Región como asunto: Africa Idioma: En Revista: Environ Health Asunto de la revista: SAUDE AMBIENTAL Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación del Aire Interior / Culinaria / Desarrollo Fetal / Contaminantes Atmosféricos / Material Particulado Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adolescent / Adult / Female / Humans / Pregnancy País/Región como asunto: Africa Idioma: En Revista: Environ Health Asunto de la revista: SAUDE AMBIENTAL Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido