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Diagnostic and Prognostic Value of Serum Endocan Levels in Patients With COVID-19.
Görgün, Selim; Cindoruk, Sener; Özgen, Emre; Yadigaroglu, Metin; Demir, Mehmet Tevfik; Yücel, Murat; Akpinar, Çetin Kürsad; Güzel, Murat.
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  • Görgün S; Department of Microbiology, Samsun Education and Research Hospital, Samsun, Turkey.
  • Cindoruk S; Department of Emergency Medicine, Samsun Education and Research Hospital, Samsun, Turkey.
  • Özgen E; Merzifon State Hospital, Emergency Medicine, Amasya, Turkey.
  • Yadigaroglu M; Department of Emergency Medicine, Samsun University, Samsun, Turkey.
  • Demir MT; Department of Emergency Medicine, Samsun Education and Research Hospital, Samsun, Turkey.
  • Yücel M; Department of Emergency Medicine, Sakarya University, Sakarya, Turkey.
  • Akpinar ÇK; Department of Neurology, Samsun Education and Research Hospital, Samsun, Turkey.
  • Güzel M; Department of Emergency Medicine, Samsun Education and Research Hospital, Samsun, Turkey.
Angiology ; 72(10): 942-946, 2021 11.
Article en En | MEDLINE | ID: mdl-34180269
We aimed to evaluate whether there was a relationship between endocan (human endothelial cell-specific molecule-1) levels and disease prognosis in patients who presented to the emergency department with coronavirus disease 2019 (COVID-19). A total of 60 patients with COVID-19 who were hospitalized from the emergency department to clinical wards and a control group consisting of healthy adult individuals (n = 28), were included in the study. The majority (93.3%) of the patients were discharged after recovery; 6.7% died. The median endocan value was 243.5 ng/mL in the patient group versus 201.5 ng/mL in the control group (P = .002). The median endocan level was 240.5 ng/mL in those discharged with recovery and 558 ng/mL in those who died (P = .001). There was no significant relationship in hospitalization duration, sex, tomography findings, and clinical outcomes. A 202 ng/mL serum endocan level had 86.7% sensitivity and 50% specificity for COVID-19. Serum endocan levels may be a useful biomarker both for the diagnosis of COVID-19 and to predict mortality.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteoglicanos / COVID-19 / Proteínas de Neoplasias Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Angiology Año: 2021 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteoglicanos / COVID-19 / Proteínas de Neoplasias Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Angiology Año: 2021 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos