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Analysis and health risk assessment of phthalate esters (PAEs) in indoor dust of preschool and elementary school centers in city of Tehran, Iran.
Abdi, Somayeh; Sobhanardakani, Soheil; Lorestani, Bahareh; Cheraghi, Mehrdad; Panahi, Homayon Ahmad.
Afiliación
  • Abdi S; Department of the Environment, College of Basic Sciences, Hamedan Branch, Islamic Azad University, Hamedan, Iran.
  • Sobhanardakani S; Department of the Environment, College of Basic Sciences, Hamedan Branch, Islamic Azad University, Hamedan, Iran. s_sobhan@iauh.ac.ir.
  • Lorestani B; Department of the Environment, College of Basic Sciences, Hamedan Branch, Islamic Azad University, Hamedan, Iran.
  • Cheraghi M; Department of the Environment, College of Basic Sciences, Hamedan Branch, Islamic Azad University, Hamedan, Iran.
  • Panahi HA; Department of Chemistry, College of Basic Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Environ Sci Pollut Res Int ; 28(43): 61151-61162, 2021 Nov.
Article en En | MEDLINE | ID: mdl-34173141
Individuals spend a lot of time indoors; thus they are generally exposed to phthalates used in consumer products. Therefore, those exposed to phthalates as indoor contaminants are at high risks. The present study was conducted to evaluate the carcinogenic and non-carcinogenic hazard of phthalate esters (PAEs), like dimethyl phthalate, diethyl phthalate, di(nbutyl) phthalate, butyl benzyl phthalate, dioctyl phthalate, and di(2-ethylhexyl) phthalate in the dust obtained from 21 schools in Tehran, in 2019. A total of 63 indoor dust specimens were obtained by a vacuum cleaner. After transferring dust samples to the laboratory, 100 mg of each sample was centrifuged and mixed with 20 ml acetone and kept through a night and ultrasonicated within 30 min. Eventually, PAEs' contents were measured via gas chromatography-mass spectrometry. Based on the findings, median concentrations of DMP, DEP, DnBP, BBP, DEHP, and DnOP were 0.90, 0.10, 6.0, 0.20, 118.30, and 4.10 mg kg-1 respectively. Moreover, the overall average daily exposure doses (ADD) of phthalate esters via dust ingestion, skin contact, and inhalation were 1.56E-03, 1.70E-06, and 1.56E-07 mg kg-1 day-1, respectively, and the lifetime average daily exposure doses (LADD) were 1.83E-04, 2.34E-08, and 2.46E-08 mg kg-1 day-1, respectively; thus ingestion of dust particles was found to be the main pathway of exposure to phthalate for non-carcinogenic and carcinogenic risks. Although based on the results, the studied samples were below the US Environmental Protection Agency threshold of 1.00E-06, due to the disadvantages of phthalates in human safety, these kinds of investigations are helpful in understanding the main ways of exposure to PAEs and providing a science-based framework for the future attempts for mitigating the PAEs indoor emissions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Ftálicos / Polvo Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Child, preschool / Humans País/Región como asunto: Asia Idioma: En Revista: Environ Sci Pollut Res Int Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Ftálicos / Polvo Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Child, preschool / Humans País/Región como asunto: Asia Idioma: En Revista: Environ Sci Pollut Res Int Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Alemania