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A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells.
Wong, Harikesh S; Park, Kyemyung; Gola, Anita; Baptista, Antonio P; Miller, Christine H; Deep, Deeksha; Lou, Meng; Boyd, Lisa F; Rudensky, Alexander Y; Savage, Peter A; Altan-Bonnet, Grégoire; Tsang, John S; Germain, Ronald N.
Afiliación
  • Wong HS; Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA. Electronic address: harikesh.wong@nih.gov.
  • Park K; Multiscale Systems Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA; Biophysics program, Institute for Physical Science and Technology, University of Maryland, College Park, MD 207
  • Gola A; Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA.
  • Baptista AP; Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA; Laboratory of Immunoregulation and Mucosal Immunology, VIB-UGhent Center for Inflammation Research, Ghent University, 9
  • Miller CH; Department of Pathology, University of Chicago, Chicago, IL 60637, USA.
  • Deep D; Howard Hughes Medical Institute, Immunology Program and Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lou M; Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA.
  • Boyd LF; Molecular Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Rudensky AY; Howard Hughes Medical Institute, Immunology Program and Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Savage PA; Department of Pathology, University of Chicago, Chicago, IL 60637, USA.
  • Altan-Bonnet G; Immunodynamics Group, Cancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Tsang JS; Multiscale Systems Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA.
  • Germain RN; Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1892, USA. Electronic address: rgermain@niaid.nih.gov.
Cell ; 184(15): 3981-3997.e22, 2021 07 22.
Article en En | MEDLINE | ID: mdl-34157301
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Activación de Linfocitos / Linfocitos T Reguladores / Retroalimentación Fisiológica / Homeostasis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Activación de Linfocitos / Linfocitos T Reguladores / Retroalimentación Fisiológica / Homeostasis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos