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Gastrointestinal symptoms in HIV-positive kidney transplant candidates and recipients from an HIV-positive donor.
Martin, C J; Veldman, F J; Labadarios, D; Ebrahim, Z; Muller, E; Kassier, S M.
Afiliación
  • Martin CJ; Department of Human Nutrition, Faculty of Health Sciences, Room 4-14, HW, Snyman Building (South), University of Pretoria, Bophelo Road, Gezina, Private Bag X323, Pretoria, 0031, South Africa. claire.martin@up.ac.za.
  • Veldman FJ; Department of Human Nutrition and Dietetics Registry, Sefako Makgatho Health Sciences University (Medunsa), P.O Box 60, Pretoria, 0204, South Africa.
  • Labadarios D; Professor Emeritus, Division of Human Nutrition, Faculty of Medicine and Health Sciences, Stellenbosch University, Private Bag X1, Matieland, Western Cape, 7602, South Africa.
  • Ebrahim Z; Division of Human Nutrition, Faculty of Medicine and Health Sciences, Stellenbosch University, Private Bag X1, Matieland, Western Cape, 7602, South Africa.
  • Muller E; Department of Surgery, University of Cape Town, Private Bag X3, Rondebosch, Cape Town, Western Cape, 7701, South Africa.
  • Kassier SM; Department of Dietetics and Human Nutrition, School of Agricultural, Earth and Environmental Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg, 3209, South Africa.
Sci Rep ; 11(1): 12592, 2021 06 15.
Article en En | MEDLINE | ID: mdl-34131245
Gastrointestinal symptoms (GIS) are common in kidney transplant candidates and recipients and may be worsened by HIV. Objective: To determine the frequency and severity of GIS in HIV-positive kidney transplant recipients from HIV-positive donors, and those waiting to receive one. A GIS rating scale (GSRS) was completed by 76 participants at baseline and at 6 months. GIS frequency was defined as having at least one symptom (GSRS > 1). Severity was indicated by the GSRS score. Transplant candidates: GIS frequency was 88.9% and 86.3% at baseline and 6 months respectively. Indigestion was the most frequent (79.6% and 66.7% at baseline and 6 months), and severe GIS (GSRS 2.3). Women reported global mean (p = 0.030) severity significantly more than men. Transplant recipients: GIS frequency was 95.2% and 76.2% at baseline and 6 months respectively. At both assessment points, indigestion occurred most frequently (85.7% and 61.9% respectively). Highest GSRS was reported for indigestion at baseline (2.33) and at 6 months (1.33). Waist circumference (WC) was positively associated with the severity of constipation GSRS. GIS are common in both groups, especially indigestions. WC in transplant recipients should be monitored.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Trasplante de Riñón / Enfermedades Gastrointestinales / Enfermedades Renales Tipo de estudio: Diagnostic_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Trasplante de Riñón / Enfermedades Gastrointestinales / Enfermedades Renales Tipo de estudio: Diagnostic_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Reino Unido