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Infections and patterns of antibiotic utilization in support and comfort care patients: A tertiary care center experience.
Mahmoud, Ebrahim; Abanamy, Reem; Binawad, Eman; Alhatmi, Hind; Alzammam, Ali; Habib, Abdulrahman; Alturaifi, Dana; Alharbi, Ahmed; Alqahtani, Hajar; Aldohayan, Mohammed.
Afiliación
  • Mahmoud E; Division of Infectious Diseases, Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia. Electronic address: emahmoud85@gmail.com.
  • Abanamy R; Division of Infectious Diseases, Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Binawad E; Division of Infectious Diseases, Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Alhatmi H; Division of Infectious Diseases, Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Alzammam A; Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Habib A; Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Alturaifi D; Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Alharbi A; Division of Infectious Diseases, Department of Medicine, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Alqahtani H; Pharmaceutical Care Department, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
  • Aldohayan M; Department of Health Informatics, CPHHI, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; Data and Business Intelligence Management Department, ISID, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
J Infect Public Health ; 14(7): 839-844, 2021 Jul.
Article en En | MEDLINE | ID: mdl-34118733
PURPOSE: Little is known regarding the burden of infections and clinical practice towards hospitalized patients with limits on life-sustaining measures. We aim to describe the infectious syndromes, clinical care, the emergence of multi-drug resistant organisms and outcomes in this population. PATIENTS AND METHODS: Retrospective cohort of patients labeled as support or comfort care in a tertiary care center between 2016-2019. RESULTS: A total of 347 patients were included with a mean age of 68.5 years, who were predominantly males (59.94%), bedbound (69.74%), on tube feeding (66.86%), and required indwelling urinary catheters (61.96%). The total number of admissions during the first year was 498, with the mean length of stay being 30 days. The number of infectious syndromes identified during that period was 821episodes, with a mean of 2 infectious syndromes per admission. The most common infection identified was pneumonia (41.66%) followed by urinary tract infections (27.16%). A total of 3891 microbiological cultures were taken with a mean of 5 cultures per infectious syndrome. The most commonly identified pathogens were Gram-negative bacteria (61.03%), with a high rate of multidrug-resistant organisms (MDROs) (48.53%). The one-year mortality was 86.4%. Using carbapenem antibiotic and pneumonia were the independent predictors used for the MDROs. CONCLUSION: Our study reflects the high burden of infections, antimicrobial resistance, and hospital admissions among a population with limited life expectancy. A consensus regarding investigating and managing of infectious syndromes, and antimicrobial prescription is needed to reduce the harms associated with overuse of antimicrobials.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección Hospitalaria / Antibacterianos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans / Male Idioma: En Revista: J Infect Public Health Asunto de la revista: DOENCAS TRANSMISSIVEIS / SAUDE PUBLICA Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección Hospitalaria / Antibacterianos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans / Male Idioma: En Revista: J Infect Public Health Asunto de la revista: DOENCAS TRANSMISSIVEIS / SAUDE PUBLICA Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido