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Listening to speech with a guinea pig-to-human brain-to-brain interface.
Richter, Claus-Peter; La Faire, Petrina; Tan, Xiaodong; Fiebig, Pamela; Landsberger, David M; Micco, Alan G.
Afiliación
  • Richter CP; Department of Otolaryngology, Northwestern University, 320 E. Superior Street, Searle 12-561, Chicago, IL, 60611, USA. cri529@northwestern.edu.
  • La Faire P; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Tech E310, Evanston, IL, 60208, USA. cri529@northwestern.edu.
  • Tan X; Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, 60208, USA. cri529@northwestern.edu.
  • Fiebig P; The Hugh Knowles Center for Clinical and Basic Science in Hearing and Its Disorders at Northwestern University, Evanston, IL, 60208, USA. cri529@northwestern.edu.
  • Landsberger DM; Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Searle Building 12-470, 303 E. Chicago Avenue, Chicago, IL, 60611-3008, USA. cri529@northwestern.edu.
  • Micco AG; Department of Otolaryngology, Northwestern University, 320 E. Superior Street, Searle 12-561, Chicago, IL, 60611, USA.
Sci Rep ; 11(1): 12231, 2021 06 10.
Article en En | MEDLINE | ID: mdl-34112826
Nicolelis wrote in his 2003 review on brain-machine interfaces (BMIs) that the design of a successful BMI relies on general physiological principles describing how neuronal signals are encoded. Our study explored whether neural information exchanged between brains of different species is possible, similar to the information exchange between computers. We show for the first time that single words processed by the guinea pig auditory system are intelligible to humans who receive the processed information via a cochlear implant. We recorded the neural response patterns to single-spoken words with multi-channel electrodes from the guinea inferior colliculus. The recordings served as a blueprint for trains of biphasic, charge-balanced electrical pulses, which a cochlear implant delivered to the cochlear implant user's ear. Study participants completed a four-word forced-choice test and identified the correct word in 34.8% of trials. The participants' recognition, defined by the ability to choose the same word twice, whether right or wrong, was 53.6%. For all sessions, the participants received no training and no feedback. The results show that lexical information can be transmitted from an animal to a human auditory system. In the discussion, we will contemplate how learning from the animals might help developing novel coding strategies.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Percepción Auditiva / Habla / Percepción del Habla / Interfaces Cerebro-Computador / Audición / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Percepción Auditiva / Habla / Percepción del Habla / Interfaces Cerebro-Computador / Audición / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido