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Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation.
Huang, Xuan; Roet, Kasper C D; Zhang, Liying; Brault, Amy; Berg, Allison P; Jefferson, Anne B; Klug-McLeod, Jackie; Leach, Karen L; Vincent, Fabien; Yang, Hongying; Coyle, Anthony J; Jones, Lyn H; Frost, Devlin; Wiskow, Ole; Chen, Kuchuan; Maeda, Rie; Grantham, Alyssa; Dornon, Mary K; Klim, Joseph R; Siekmann, Marco T; Zhao, Dongyi; Lee, Seungkyu; Eggan, Kevin; Woolf, Clifford J.
Afiliación
  • Huang X; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Roet KCD; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Zhang L; Medicine Design, Pfizer, Cambridge, MA 02139, USA.
  • Brault A; Medicine Design, Pfizer, Groton, CT 06340, USA.
  • Berg AP; Rare Disease Research Unit, Pfizer, Cambridge, MA 02139, USA.
  • Jefferson AB; Pfizer Centers for Therapeutic Innovation (CTI), San Francisco, CA 94080, USA.
  • Klug-McLeod J; Medicine Design, Pfizer, Cambridge, MA 02139, USA.
  • Leach KL; Pfizer Centers for Therapeutic Innovation (CTI), Cambridge, MA 02139, USA.
  • Vincent F; Medicine Design, Pfizer, Groton, CT 06340, USA.
  • Yang H; Pfizer Centers for Therapeutic Innovation (CTI), Cambridge, MA 02139, USA.
  • Coyle AJ; Pfizer Centers for Therapeutic Innovation (CTI), Cambridge, MA 02139, USA.
  • Jones LH; Medicine Design, Pfizer, Cambridge, MA 02139, USA.
  • Frost D; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Wiskow O; Department of Stem Cell and Regenerative Biology, Department of Molecular and Cellular Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
  • Chen K; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Maeda R; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Grantham A; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Dornon MK; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Klim JR; Department of Stem Cell and Regenerative Biology, Department of Molecular and Cellular Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
  • Siekmann MT; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Zhao D; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Lee S; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
  • Eggan K; Department of Stem Cell and Regenerative Biology, Department of Molecular and Cellular Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
  • Woolf CJ; F.M. Kirby Neurobiology Center, Boston Children's Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: clifford.woolf@childrens.harvard.edu.
Cell Rep ; 35(10): 109224, 2021 06 08.
Article en En | MEDLINE | ID: mdl-34107252

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esclerosis Amiotrófica Lateral Límite: Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esclerosis Amiotrófica Lateral Límite: Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos