Small molecule-mediated modulation of ubiquitination and neddylation improves HSC function ex vivo.

Albayrak, Esra; Uslu, Merve; Akgol, Sezer; Tuysuz, Emre Can; Kocabas, Fatih

Albayrak, Esra; Uslu, Merve; Akgol, Sezer; Tuysuz, Emre Can; Kocabas, Fatih.

Afiliación

Albayrak E; Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.
Uslu M; Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.
Akgol S; Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.
Tuysuz EC; Department of Medical Genetics, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.
Kocabas F; Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.

J Cell Physiol ; 236(12): 8122-8136, 2021 12.

Article en En | MEDLINE | ID: mdl-34101829

Asunto(s)

Proliferación Celular/fisiología; Células Endoteliales/citología; Células Madre Hematopoyéticas/metabolismo; Ubiquitinación/fisiología; Animales; Ciclo Celular/fisiología; Humanos; Ratones; Proteína NEDD8/metabolismo; Proteínas Quinasas Asociadas a Fase-S/metabolismo

Palabras clave

HSC; neddylation; small molecules; ubiquitination

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Células Endoteliales / Proliferación Celular / Ubiquitinación Límite: Animals / Humans Idioma: En Revista: J Cell Physiol Año: 2021 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos

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