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Preclinical immunogenicity testing using anti-drug antibody analysis of GX-G3, Fc-fused recombinant human granulocyte colony-stimulating factor, in rat and monkey models.
Kim, Yun Jung; Koh, Eun Mi; Song, Chi Hun; Byun, Mi Sun; Choi, Yu Ri; Jeon, Eun-Jeong; Hwang, Kyunghwa; Kim, Sang Kyum; Yang, Sang In; Jung, Kyung Jin.
Afiliación
  • Kim YJ; Genexine, Inc, Korea Bio Park, Seongnam, 13488, Republic of Korea.
  • Koh EM; Bioanalytical and Immunoanalytical Research Group, Department of Advanced Toxicology Research, Korea Institute of Toxicology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea.
  • Song CH; Bioanalytical and Immunoanalytical Research Group, Department of Advanced Toxicology Research, Korea Institute of Toxicology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea.
  • Byun MS; College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34131, Republic of Korea.
  • Choi YR; Genexine, Inc, Korea Bio Park, Seongnam, 13488, Republic of Korea.
  • Jeon EJ; Genexine, Inc, Korea Bio Park, Seongnam, 13488, Republic of Korea.
  • Hwang K; Bioanalytical and Immunoanalytical Research Group, Department of Advanced Toxicology Research, Korea Institute of Toxicology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea.
  • Kim SK; Jeonbuk Analytical Research Group, In Vivo Hazard Evaluation and Research Division, Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Jeollabuk-do, 56212, Republic of Korea.
  • Yang SI; College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34131, Republic of Korea. sangkim@cnu.ac.kr.
  • Jung KJ; Genexine, Inc, Korea Bio Park, Seongnam, 13488, Republic of Korea. siyang@genexine.com.
Sci Rep ; 11(1): 12004, 2021 06 07.
Article en En | MEDLINE | ID: mdl-34099775
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Fragmentos Fc de Inmunoglobulinas / Factor Estimulante de Colonias de Granulocitos / Factores Inmunológicos / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Fragmentos Fc de Inmunoglobulinas / Factor Estimulante de Colonias de Granulocitos / Factores Inmunológicos / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido