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Recreational ketamine-related deaths notified to the National Programme on Substance Abuse Deaths, England, 1997-2019.
Corkery, John Martin; Hung, Wan-Chu; Claridge, Hugh; Goodair, Christine; Copeland, Caroline S; Schifano, Fabrizio.
Afiliación
  • Corkery JM; Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, Department of Clinical, Pharmaceutical and Biological Sciences, University of Hertfordshire, Hatfield, Hertfordshire, UK.
  • Hung WC; Institute of Pharmaceutical Sciences, King's College London, London, UK.
  • Claridge H; National Programme on Substance Abuse Deaths, St George's, University of London, London, UK.
  • Goodair C; Population Health Research Institute, St George's, University of London, London, UK.
  • Copeland CS; National Programme on Substance Abuse Deaths, St George's, University of London, London, UK.
  • Schifano F; Population Health Research Institute, St George's, University of London, London, UK.
J Psychopharmacol ; 35(11): 1324-1348, 2021 11.
Article en En | MEDLINE | ID: mdl-34092131
BACKGROUND: Ketamine is a phencyclidine derivative with dissociative anaesthetic properties. Increasing numbers of individuals in England take ketamine recreationally. Information on deaths arising from such use in England is presented. METHODS: Cases were extracted on 31 January 2020 from the National Programme on Substance Abuse Deaths database, based on text searches of the cause of death, coroner's verdict and positive toxicology results for the terms 'ketamine' or 'norketamine'. FINDINGS: During 1997-2005, there were <5 deaths p.a. in which ketamine was implicated. Numbers increased until 2009 (21), plateauing until 2016; thereafter, deaths have risen to about 30 p.a. Decedents' characteristics (N = 283): male 84.1%, mean age 31.2 (SD 10.0) years, employed 56.5%, drug use history 79.6% and living with others 60.3%. Ketamine was detected with other substances in most cases. Main (74.6%) underlying cause of death was accidental poisoning. Ketamine may have impaired judgement in other cases. CONCLUSIONS: Although controlled, recreational ketamine use and related fatalities continue to increase. Consumers need to be more aware of the potentially fatal risks they face.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Drogas Ilícitas / Trastornos Relacionados con Sustancias / Uso Recreativo de Drogas / Ketamina / Anestésicos Disociativos Tipo de estudio: Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Psychopharmacol Asunto de la revista: PSICOFARMACOLOGIA Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Drogas Ilícitas / Trastornos Relacionados con Sustancias / Uso Recreativo de Drogas / Ketamina / Anestésicos Disociativos Tipo de estudio: Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Psychopharmacol Asunto de la revista: PSICOFARMACOLOGIA Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos