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Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants.
Ku, Zhiqiang; Xie, Xuping; Hinton, Paul R; Liu, Xinli; Ye, Xiaohua; Muruato, Antonio E; Ng, Dean C; Biswas, Sujit; Zou, Jing; Liu, Yang; Pandya, Deepal; Menachery, Vineet D; Rahman, Sachi; Cao, Yu-An; Deng, Hui; Xiong, Wei; Carlin, Kevin B; Liu, Junquan; Su, Hang; Haanes, Elizabeth J; Keyt, Bruce A; Zhang, Ningyan; Carroll, Stephen F; Shi, Pei-Yong; An, Zhiqiang.
Afiliación
  • Ku Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Xie X; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
  • Hinton PR; IGM Biosciences, Mountain View, CA, USA.
  • Liu X; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA.
  • Ye X; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Muruato AE; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
  • Ng DC; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
  • Biswas S; IGM Biosciences, Mountain View, CA, USA.
  • Zou J; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA.
  • Liu Y; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
  • Pandya D; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
  • Menachery VD; IGM Biosciences, Mountain View, CA, USA.
  • Rahman S; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
  • Cao YA; IGM Biosciences, Mountain View, CA, USA.
  • Deng H; IGM Biosciences, Mountain View, CA, USA.
  • Xiong W; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Carlin KB; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Liu J; IGM Biosciences, Mountain View, CA, USA.
  • Su H; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Haanes EJ; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Keyt BA; IGM Biosciences, Mountain View, CA, USA.
  • Zhang N; IGM Biosciences, Mountain View, CA, USA. bkeyt@igmbio.com.
  • Carroll SF; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. Ningyan.Zhang@uth.tmc.edu.
  • Shi PY; IGM Biosciences, Mountain View, CA, USA. scarroll@igmbio.com.
  • An Z; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA. peshi@utmb.edu.
Nature ; 595(7869): 718-723, 2021 07.
Article en En | MEDLINE | ID: mdl-34082438
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina M / SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina M / SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido