Local Colonic Administration of a Serine Protease Inhibitor Improves Post-Inflammatory Visceral Hypersensitivity in Rats.

Hanning, Nikita; De Bruyn, Michelle; Ceuleers, Hannah; Boogaerts, Tim; Berg, Maya; Smet, Annemieke; De Schepper, Heiko U; Joossens, Jurgen; van Nuijs, Alexander L N; De Man, Joris G; Augustyns, Koen; De Meester, Ingrid; De Winter, Benedicte Y

Hanning, Nikita; De Bruyn, Michelle; Ceuleers, Hannah; Boogaerts, Tim; Berg, Maya; Smet, Annemieke; De Schepper, Heiko U; Joossens, Jurgen; van Nuijs, Alexander L N; De Man, Joris G; Augustyns, Koen; De Meester, Ingrid; De Winter, Benedicte Y.

Afiliación

Hanning N; Laboratory of Experimental Medicine and Pediatrics (LEMP), University of Antwerp, 2610 Wilrijk, Belgium.
De Bruyn M; Infla-Med, Centre of Excellence, University of Antwerp, 2610 Wilrijk, Belgium.
Ceuleers H; Infla-Med, Centre of Excellence, University of Antwerp, 2610 Wilrijk, Belgium.
Boogaerts T; Laboratory of Medical Biochemistry, University of Antwerp, 2610 Wilrijk, Belgium.
Berg M; Laboratory of Experimental Medicine and Pediatrics (LEMP), University of Antwerp, 2610 Wilrijk, Belgium.
Smet A; Infla-Med, Centre of Excellence, University of Antwerp, 2610 Wilrijk, Belgium.
De Schepper HU; Toxicological Centre, University of Antwerp, 2610 Wilrijk, Belgium.
Joossens J; Infla-Med, Centre of Excellence, University of Antwerp, 2610 Wilrijk, Belgium.
van Nuijs ALN; Laboratory of Experimental Medicine and Pediatrics (LEMP), University of Antwerp, 2610 Wilrijk, Belgium.
De Man JG; Infla-Med, Centre of Excellence, University of Antwerp, 2610 Wilrijk, Belgium.
Augustyns K; Laboratory of Experimental Medicine and Pediatrics (LEMP), University of Antwerp, 2610 Wilrijk, Belgium.
De Meester I; Infla-Med, Centre of Excellence, University of Antwerp, 2610 Wilrijk, Belgium.
De Winter BY; Department of Gastroenterology and Hepatology, Antwerp University Hospital (UZA), 2650 Edegem, Belgium.

Pharmaceutics ; 13(6)2021 May 29.

Article en En | MEDLINE | ID: mdl-34072320

Palabras clave

elastase; irritable bowel syndrome; proteolytic activity; serine proteases; trypsin; visceral hypersensitivity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2021 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Suiza

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