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Residual SYNTAX II Score and long-term outcomes post-ST-elevation myocardial infarction in an urban US cohort: the Montefiore STEMI Registry.
Bortnick, Anna E; Shitole, Sanyog G; Hashim, Hayder; Khullar, Pankaj; Park, Michael; Weinreich, Michael; Seibert, Stephen; Rauch, Judah; Weisz, Giora; Kizer, Jorge R.
Afiliación
  • Bortnick AE; Department of Medicine, Division of Cardiology.
  • Shitole SG; Department of Medicine, Division of Geriatrics, Montefiore Medical Center.
  • Hashim H; Albert Einstein College of Medicine, Bronx, New York.
  • Khullar P; Department of Medicine, Cardiology Section, San Francisco Veterans Affairs Health Care System, and Department of Medicine, University of California San Francisco, San Francisco, California.
  • Park M; Division of Cardiology, Department of Medicine, MedStar Washington Hospital Center and Georgetown University, Washington DC.
  • Weinreich M; Sorin Medical, P.C., Brooklyn.
  • Seibert S; Division of Cardiovascular Medicine, Department of Medicine, University at Buffalo, Buffalo, New York.
  • Rauch J; Department of Medicine, Division of Cardiology.
  • Weisz G; Department of Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio.
  • Kizer JR; Department of Medicine, Division of Cardiology.
Coron Artery Dis ; 33(3): 206-212, 2022 05 01.
Article en En | MEDLINE | ID: mdl-34049323
BACKGROUND: Higher residual anatomic disease was associated with increased mortality in a recent randomized controlled trial of revascularization after ST-elevation myocardial infarction (STEMI). Less is known about the impact of residual disease post-STEMI in race-ethnic minorities. METHODS: Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX)- II (SS-II) score is an established scoring method for anatomic disease and prevalent co-morbidities to describe patient complexity. We evaluated residual (r) SS-II in 165 patients from a single center urban US registry (n = 1208) presenting for primary percutaneous coronary intervention of STEMI and treated for 3-vessel or left main and any combination of 0, 1, 2 or 3-vessel disease. RESULTS: The median age was 62 years (IQR 52-70), 29.1% women, 44.9% Hispanic/Latino and 19.4% non-Hispanic Black. Over median of 4.9 years (IQR 2.9-6.3), higher rSS-II was associated with increased death [hazard ratio 2.46 per SD increment in log rSS-II (~five-fold increment on the original scale) 95% CI 1.51, 3.99], death or all-cause readmission (hazard ratio 1.37 per SD increment in log rSS-II 95% CI, 1.11-1.70) and death or cardiovascular disease readmission (hazard ratio 1.46 per SD increment in log rSS-II 95% CI, 1.14-1.88). rSS-II was higher in older women with more co-morbidities, but not different by race-ethnicity. CONCLUSIONS: In summary, higher rSS-II was associated with long-term outcomes post-STEMI in a prospective urban, minority cohort, suggesting a potential role for risk stratification with this measure in a non-trial setting.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intervención Coronaria Percutánea / Infarto del Miocardio con Elevación del ST Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Coron Artery Dis Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intervención Coronaria Percutánea / Infarto del Miocardio con Elevación del ST Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Coron Artery Dis Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido