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Translational biomarkers in the era of precision medicine.
Bravo-Merodio, Laura; Acharjee, Animesh; Russ, Dominic; Bisht, Vartika; Williams, John A; Tsaprouni, Loukia G; Gkoutos, Georgios V.
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  • Bravo-Merodio L; Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham, United Kingdom; Institute of Translational Medicine, University of Birmingham, Birmingham, United Kingdom.
  • Acharjee A; Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham, United Kingdom; Institute of Translational Medicine, University of Birmingham, Birmingham, United Kingdom; NIHR Surgical Reconstruction and Microbiology Research Centre, University Hospi
  • Russ D; Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham, United Kingdom; Institute of Translational Medicine, University of Birmingham, Birmingham, United Kingdom.
  • Bisht V; Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham, United Kingdom; Institute of Translational Medicine, University of Birmingham, Birmingham, United Kingdom.
  • Williams JA; Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham, United Kingdom; Medical Research Council Harwell Institute, Harwell Campus, Oxfordshire, United Kingdom.
  • Tsaprouni LG; Birmingham City University, Centre for Life and Sport Science, Birmingham, United Kingdom.
  • Gkoutos GV; Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham, United Kingdom; Institute of Translational Medicine, University of Birmingham, Birmingham, United Kingdom; NIHR Surgical Reconstruction and Microbiology Research Centre, University Hospi
Adv Clin Chem ; 102: 191-232, 2021.
Article en En | MEDLINE | ID: mdl-34044910
In this chapter we discuss the past, present and future of clinical biomarker development. We explore the advent of new technologies, paving the way in which health, medicine and disease is understood. This review includes the identification of physicochemical assays, current regulations, the development and reproducibility of clinical trials, as well as, the revolution of omics technologies and state-of-the-art integration and analysis approaches.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Medicina de Precisión Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Adv Clin Chem Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Medicina de Precisión Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Adv Clin Chem Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos