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PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain.
Schaler, Ari W; Runyan, Avery M; Clelland, Catherine L; Sydney, Eric J; Fowler, Stephanie L; Figueroa, Helen Y; Shioda, Seiji; Santa-Maria, Ismael; Duff, Karen E; Myeku, Natura.
Afiliación
  • Schaler AW; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Runyan AM; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Clelland CL; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Sydney EJ; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Fowler SL; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Figueroa HY; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Shioda S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Santa-Maria I; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Duff KE; U.K. Dementia Research Institute, University College London, London WC1E 6BT, UK.
  • Myeku N; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY 10032, USA.
Sci Transl Med ; 13(595)2021 05 26.
Article en En | MEDLINE | ID: mdl-34039738

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas tau / Tauopatías Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas tau / Tauopatías Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos