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Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models.
Zhu, Qi; Zhuang, Xu-Xu; Chen, Jia-Yue; Yuan, Ning-Ning; Chen, Yan; Cai, Cui-Zan; Tan, Jie-Qiong; Su, Huan-Xing; Lu, Jia-Hong.
Afiliación
  • Zhu Q; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
  • Zhuang XX; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
  • Chen JY; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
  • Yuan NN; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
  • Chen Y; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
  • Cai CZ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
  • Tan JQ; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha 410078, China.
  • Su HX; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
  • Lu JH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China. Electronic address: jiahonglu@um.edu.mo.
Phytomedicine ; 87: 153578, 2021 Jul.
Article en En | MEDLINE | ID: mdl-34038839
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Fenantridinas / Proteínas Quinasas Dependientes de AMP Cíclico / Alcaloides de Amaryllidaceae / Alfa-Sinucleína Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Fenantridinas / Proteínas Quinasas Dependientes de AMP Cíclico / Alcaloides de Amaryllidaceae / Alfa-Sinucleína Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania